Características clínicas demográficas em 99 episódios de febre reumática no Acre, Amazônia Brasileira

Borges, Fátima; Barbosa, Maria Luiza A.; Borges, Renata Beyruth; Pinheiro, Olívia C.; Cardoso, Carlos Roberto; Bastos, Claudilson; Aras, Roque

doi:10.1590/s0066-782x2005000200004

Cited by 10 publications

(21 citation statements)

References 9 publications

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“…Frequency of chorea (28%) was higher than that reported in the international literature, 2,4,6 with 15%-20% estimates, but was similar to the results reported in the Brazilian series, 11,14,22 nearly 30%. Chorea is characterized by involuntary movements of extremities, muscular hypotonia, dysartria, gait disturbance, and tics, as well as behavioral manifestations.…”

supporting

confidence: 84%

“…In another Brazilian series from the state of Acre, 14 as well as others reported from Liban 12 and Canada, 17 carditis was the most frequent major sign. Arthritis had migratory or additive pattern in most of our cases, affecting predominantly large joints as described originally in the 1950's.…”

mentioning

confidence: 69%

“…A systematic evaluation of patients care is important to defi ne further strategy for disease control and treatment. A systematic comparison of the present series with previously published series [11][12][13][14][15][16][17][18] is presented in the Table 2. Onset age was comparable.…”

Section: Discussionmentioning

confidence: 96%

“…In our series, only 58.2% had high antistreptolysin-O titres. A comparison with previous reported series described in Table 2, [11][12][13][14][15][16][17][18] in addition to a 24 comparing all Brazilian series published since the 1980's, indicated a wide variation, 48.7%-84.5%, from different studies in many parts of the country. Antistreptolysin-O rising titres in RF cases from our unit were previously examined, stressing the importance of serial determination over the fi rst two months.…”

mentioning

confidence: 78%

“…25 The tests of acute phase response indicated high erythrocyte sedimentation rate in 58.3% and C-reactive protein in 45.9%, and again a wide variation is observed in the published series. [11][12][13][14][15][16][17][18]24 It is possible that different laboratory techniques might have infl uenced these results in the same way for antistreptolysin-O, but it was not possible to reach a conclusion, due to the retrospective approach.…”

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confidence: 99%

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Apresentação e desfecho da febre reumática em uma série de casos

Carvalho¹,

Dalben²,

Corrente³

et al. 2012

Rev. Bras. Reumatol.

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Objective: To assess the clinical characteristics and outcome of a rheumatic fever case-series from a referral hospital over the last 20 years. Patients and methods: Patients under the age of 18 years, diagnosed with rheumatic fever between 1986 and 2007 were retrospectively assessed to estimate the carditis and relapse rates, by use of descriptive and survival analysis. Results: Of 178 cases identifi ed, 134 were included. During the acute phase, 66.4% had polyarthritis, 56.8% had carditis, 28.6% had chorea, 1.5% had subcutaneous nodules, and 1.5% had erythema marginatum. The association of carditis and arthritis occurred in 40%. Carditis and chorea were more frequent among female gender. High antistreptolysin-O titres were found in 58.3%, and family history of rheumatic fever, in 14.5%. Mean follow-up was 6.8 years (1.1 to 16.9). Relapse was observed in 15%, hospital admissions in 27.6%, and follow-up discontinuation in 47.4% after a mean of 5.1 years. Carditis and relapse probabilities were 17.5% and 13.2%, respectively, fi ve years after the initial attack. Conclusion: The risk of carditis and relapse of rheumatic fever was higher within the fi rst fi ve years. Follow-up discontinuation was frequent, pointing to the need of measures to improve adherence to prophylaxis and follow-up.

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supporting

confidence: 84%

mentioning

confidence: 69%

Section: Discussionmentioning

confidence: 96%

mentioning

confidence: 78%

mentioning

confidence: 99%

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Apresentação e desfecho da febre reumática em uma série de casos

Carvalho¹,

Dalben²,

Corrente³

et al. 2012

Rev. Bras. Reumatol.

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Cardiomyopathy, adult valve disease and heart failure in South America

Bocchi¹,

Guimarães

Tarasoutshi

et al. 2008

Heart

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Continued assessment of temporal trends in mortality and epidemiology of specific cardiovascular diseases in South America is needed to provide a scientific basis for rational allocation of the limited healthcare resources and introduction of strategies to reduce risk and predict the future burden of cardiovascular disease. The epidemiology of cardiomyopathies, adult valve disease and heart failure (HF) in South America is reviewed here. Diseases of the circulatory system are the main cause of death based on data from about 50% of the South American population. Among the cardiovascular causes of death, cerebrovascular disease is predominant followed by ischaemic heart disease, other heart diseases and hypertensive disease. Of note, cerebrovascular disease is the main cause of death in women, and race also influenced cardiovascular mortality rates. HF is the most important cardiovascular reason for admission to hospital due to cardiovascular disease of ischaemic, idiopathic dilated cardiomyopathic, valvular, hypertensive and chagasic aetiologies. Also, mortality due to HF is high, especially owing to Chagas' disease. HF and aetiologies associated with HF are responsible for 6.3% of deaths. Rheumatic fever is the leading cause of valvular heart disease. The findings have important public health implications because the allocation of healthcare resources, and strategies to reduce the risk of HF should also consider controlling Chagas' disease and rheumatic fever in South American countries.

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Aspectos epidemiológicos da fibrilação atrial

Justo

Silva

2014

Rev. Med. (São Paulo)

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Atrial fibrillation (AF) is the most common cardiac arrhythmia clinically relevant. In this project we studied the disease based on epidemiological characteristics. Articles from 1947 to April of 2013 were reviewed, matching "atrial fibrillation" and "epidemiology", "screening", "mortality", "morbidity", "risk factors" among others in an international database, taking into consideration impact factor and English language. Results are presented as following: Epidemiological Profile, that analyses prevalence and incidence of AF regarding to age, gender, risk factors and etiology; Morbimortality Profile, that investigates the most commonly associated diseases and their multivariate mortality rates; and Hospitalization Profile, that shows hospitalized AF patients' characteristics and length of stay. Thus, it has been shown that: 1. The increase in life expectancy is accompanied by an increase in AF incidence. The prevalence is significantly higher in men and in older people; 2. Cardiovascular diseases are associated conditions that worsen the AF' severity and mortality rates; 3. There was an increase in hospital expenses and in hospitalizations assigned to AF, in spite of a decrease in hospitalizations in general.

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Características clínicas demográficas em 99 episódios de febre reumática no Acre, Amazônia Brasileira

Abstract: Rheumatic carditis was the most common manifestation of rheumatic fever, predominant in the group with a racial mixture of Caucasian and Indian (60.6%). Low compliance with antibiotic therapy contributed to the recurrence of the disease and to cardiac sequelae.

Cited by 10 publications

References 9 publications

Apresentação e desfecho da febre reumática em uma série de casos

Apresentação e desfecho da febre reumática em uma série de casos

Cardiomyopathy, adult valve disease and heart failure in South America

Aspectos epidemiológicos da fibrilação atrial

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