Níveis de hormônios tireoideanos em pacientes com dissecção aórtica: comparação com controles e correlação com a porcentagem de área da camada média composta por depósitos mixóides
Abstract:Our data suggest that serum levels of thyroid hormones have no relation with the myxoid content in the aortic media in cases of aortic dissection.
“…The proportion of ATAAD patients with low T3 levels was as high as 79.5% (70/88), which was similar to a previous report (23). However, the clinical significance of thyroid hormone levels in ATAAD has not yet been confirmed (24). The relationship between low T3 levels and vulnerable renal function has been observed in patients with chronic clinical hypothyroidism and renal failure (17).…”
“…The proportion of ATAAD patients with low T3 levels was as high as 79.5% (70/88), which was similar to a previous report (23). However, the clinical significance of thyroid hormone levels in ATAAD has not yet been confirmed (24). The relationship between low T3 levels and vulnerable renal function has been observed in patients with chronic clinical hypothyroidism and renal failure (17).…”
“…Although the pathogenesis of aortic dissection has not been totally clarified 4 , a weakness of the wall is probably present, linked to alterations in the extracellular matrix, including a reduction in collagen 5 . That underlying condition is reinforced by the fact that the artery might have more than one dissection.…”
T3 was downregulated in acute aortic dissection. Low T3 level was a risk factor for in-hospital death and acute renal failure in patients with acute aortic dissection.
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