Case 5/2001 - Heart failure and insufficiency of the aortic and mitral valves in a 68-year-old woman with rheumatoid arthritis

Killinger, Luciano Campos; Gutierrez, Paulo Sampaio

doi:10.1590/s0066-782x2001001000007

Cited by 2 publications

(1 citation statement)

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“…In other studies, the patient's aortic valve was calcified, also suggesting a degenerative etiology. Besides, diabetes and hypercholesterolemia are risk factors for degenerative aortic valve injury, which is usually associated to calcification of the mitral ring and coronary arteries, but rarely to aortic valve failure [6]. In our case, histological proofs were not available.…”

Section: Discussionmentioning

confidence: 72%

Aortic regurgitation in rheumatoid arthritis: A case report

Mabrouk¹

2022

J Clin Images Med Case Rep

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Recent epidemiological studies have reported an increase in cardiovascular morbidity and mortality in Rheumatoid Arthritis (RA). The most common cardiac involvement in RA is pericarditis, followed by myocarditis, coronary vasculitis, then aortitis. However, valvular heart disease has been rarely reported especially the aortic one. We report here a case of RA associated with a severe aortic insufficiency (AI) with a thickened aortic valve on the echocardiography and aortic regurgitation. All causes of AI other than RA were excluded before concluding to a complication of cardiac RA complication. In long-standing RA, echocardiography should be assessed if patient complain about dyspnea in order to not overlook the valvular lesions.

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Section: Discussionmentioning

confidence: 72%

Aortic regurgitation in rheumatoid arthritis: A case report

Mabrouk¹

2022

J Clin Images Med Case Rep

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Rheumatoid arthritis mimicking infective endocarditis with severe aortic regurgitation and aortic root abscess: a case report

Kyhl

Rasmussen

Lindhardsen

et al. 2021

European Heart Journal - Case Reports

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Background Rheumatoid arthritis (RA) may involve the cardiovascular system and can cause significant structural cardiac disease. RA mimicking infective endocarditis (IE) is rarely reported. Case summary A 46-year-old man with a medical history of seropositive RA attended a planned outpatient visit for infliximab treatment. The pre-infusion examination revealed a pulse of 41 b.p.m. and the following electrocardiogram showed 3rd degree atrioventricular block. A temporary pacemaker was inserted, and subsequent transthoracic and transoesophageal echocardiograms showed severe aortic valve regurgitation with thickened cusps and thus raised suspicion of infective aortic endocarditis with root abscess. The patient underwent surgery with valve and root replacement the next day. What was thought to be IE, proved to be suppurative and granulomatous inflammation with sporadic necrosis and hyaline fibrosis, compatible with a rheumatoid nodule linked to the patient’s RA diagnosis. Discussion IE is a disease with high mortality and morbidity. In some cases of IE perivalvular cavities develop, most commonly abscesses and/or pseudoaneurysms, which necessitates surgery. Several conditions may mimic IE: for example, malignant and benign tumours, rheumatic diseases, and common age-related valve calcification. In patients with valvular vegetations that are ‘culture-negative’, alternative pathologies should be considered.

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Case 5/2001 - Heart failure and insufficiency of the aortic and mitral valves in a 68-year-old woman with rheumatoid arthritis

Cited by 2 publications

References 0 publications

Aortic regurgitation in rheumatoid arthritis: A case report

Aortic regurgitation in rheumatoid arthritis: A case report

Rheumatoid arthritis mimicking infective endocarditis with severe aortic regurgitation and aortic root abscess: a case report

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