Methodological and statistical topics in randomized controlled clinical trials

Escosteguy, Cláudia Caminha

doi:10.1590/s0066-782x1999000200002

Cited by 20 publications

(6 citation statements)

References 7 publications

(2 reference statements)

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“…According to Escosteguy (1999), studies with a randomized design are the best source of scientific evidence available and the best source for determining an intervention's efficacy. As such, they are considered the gold standard of scientific research.…”

Section: Methodsmentioning

confidence: 99%

“…Nevertheless, even though the descriptor “randomized controlled trials” was used in the search strategy, we decided to include articles with other designs in order to include a greater number of publications, as this is a recent subject and publications in the field are scarce. To build the results, only studies with a randomized controlled design were evaluated for their quality (Escosteguy, 1999). …”

Section: Methodsmentioning

confidence: 99%

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Optimism and Hope in Chronic Disease: A Systematic Review

et al. 2017

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There is a growing recognition that positive psychological functioning (which includes constructs such as optimism and hope) influences health. However, the understanding of these underlying mechanisms in relation to health is limited. Therefore, this review sought to identify what the scientific literature says about the influence of optimism and hope on chronic disease treatment. A search was conducted in the PsycINFO, Scopus, Pubmed, and Web of Science databases using the indexing terms optimism, hope, chronic diseases, randomized controlled trial, and treatment between 1998 and 2015. In the articles, we identified the most studied diseases in context, the assessment instruments used, the participant characteristics investigated, the results found, and the publication dates. From our analysis of the articles that met our inclusion criteria, it appears that the study of these constructs is recent and there is evidence that individuals with greater optimism and hope seek to engage in healthier behaviors, regardless of their clinical status, and that this contributes to chronic disease treatment. More research is needed so that targeted interventions can be carried out effectively in chronic disease treatment.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Optimism and Hope in Chronic Disease: A Systematic Review

et al. 2017

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“…Systematic reviews, to be effective, must include only randomized controlled studies, which are high-quality evidence. 23 Exclusion criteria were: studies that did not show any clear methodological definition and those whose main outcome was not focused on the smell or taste of the subjects.…”

Section: Review Literaturementioning

confidence: 99%

Tobacco Influence on Taste and Smell: Systematic Review of the Literature

Ré

Gurgel

Buffon

et al. 2017

Int Arch Otorhinolaryngol

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Introduction In Brazil, estimates show that 14.7% of the adult population smokes, and changes in smell and taste arising from tobacco consumption are largely present in this population, which is an aggravating factor to these dysfunctions. Objectives The objective of this study is to systematically review the findings in the literature about the influence of smoking on smell and taste. Data Synthesis Our research covered articles published from January 1980 to August 2014 in the following databases: MEDLINE (accessed through PubMed), LILACS, Cochrane Library, and SciELO. We conducted separate lines of research: one concerning smell and the other, taste. We analyzed all the articles that presented randomized controlled studies involving the relation between smoking and smell and taste. Articles that presented unclear methodologies and those whose main results did not target the smell or taste of the subjects were excluded. Titles and abstracts of the articles identified by the research strategy were evaluated by researchers. We included four studies, two of which were exclusively about smell: the first noted the relation between the perception of puff strength and nicotine content; the second did not find any differences in the thresholds and discriminative capacity between smokers and nonsmokers. One article considered only taste and supports the relation between smoking and flavor, another considered both sensory modalities and observes positive results toward the relation immediately after smoking cessation. Conclusion Three of the four studies presented positive results for the researched variables.

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“…O estudo tratou-se de um ensaio clínico controlado. Este tipo de estudo verifica o efeito de determinada intervenção em um grupo experimental, geralmente terapêutica, quando comparada a controles (ESCOSTEGUY, 1999). O projeto foi avaliado e aprovado pelo Comitê de Ética do ISECENSA, com parecer consubstanciado nº 3.464.436, e registro na plataforma brasileira de registro de Ensaios Clínicos (Re-BEC) com nº UTN: U1111-1249-0494.…”

Section: Métodounclassified

Exercícios para um envelhecimento saudável

Pernambuco¹,

Vale²,

Dantas³

2023

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Esta obra apresenta produtos de pesquisa de Mestrado e Doutorado do Laboratório de Biociências da Motricidade Humana, que geraram de teses de doutorado dos autores e orientados pelos organizadores com o principal objetivo a melhora da qualidade de vida da população IDOSA. Esta parcela da população que mais necessita se manter autônoma física e cognitivamente. A participação de programas de exercícios tem sido a estratégia mais efetiva, de baixo custo e divertida.

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Methodological and statistical topics in randomized controlled clinical trials

Abstract: Methodological and Statistical Topics in Randomized Controlled Clinical Trials Lecture Escosteguy CC Methodology of randomized clinical trials Arq Bras Cardiol volume 72, (nº 2), 1999 volume 72, (nº 2), 1999 Escosteguy CC Methodology of randomized clinical trials

Cited by 20 publications

References 7 publications

Optimism and Hope in Chronic Disease: A Systematic Review

Optimism and Hope in Chronic Disease: A Systematic Review

Tobacco Influence on Taste and Smell: Systematic Review of the Literature

Exercícios para um envelhecimento saudável

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