Notification of the first isolation of Cacipacore virus in a human in the State of Rondônia, Brazil

Batista, Weber Cheli; Tavares, Glauciane da Silva Bifano; Vieira, Deusilene Souza; Honda, Eduardo Rezende; Pereira, Soraya Santos; Tada, Mauro Shugiro

doi:10.1590/s0037-86822011000400028

Cited by 25 publications

(13 citation statements)

References 8 publications

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“…The detection of antibodies to Cacipacoré virus in a primate from the municipality of Aquidauana, together with a previous report of virus isolation on a farm in the State of Rondônia ( northern Brazil, bordering Bolivia) 26 , suggests that the State of Mato Grosso do Sul could enable the spread of this arbovirus because the BR-262 highway connects the Southeast region of Brazil to the Bolivian border.…”

Section: Discussionmentioning

confidence: 72%

Detection of arboviruses of public health interest in free-living New World primates (Sapajus spp.; Alouatta caraya) captured in Mato Grosso do Sul, Brazil

Batista

Andreotti

Almeida

et al. 2013

Rev. Soc. Bras. Med. Trop.

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Introduction:A sero-epidemiological survey was undertaken to detect the circulation of arboviruses in free-living non-human primates. Methods: Blood samples were obtained from 16 non-human primates ( 13 Sapajus spp. and three Alouatta caraya) that were captured using terrestrial traps and anesthetic darts in woodland regions in the municipalities of Campo Grande, Aquidauana, Jardim, Miranda and Corumbá in the State of Mato Grosso do Sul, Brazil. The samples were sent to the Instituto Evandro Chagas (IEC) in Ananindeua, Pará, Brazil, to detect antibodies against 19 species of arboviruses using a hemagglutination inhibition test (HI). Results: Of the 16 primates investigated in the present study, fi ve (31.2%) were serologically positive for an arbovirus. Of these fi ve, two (12.5%) exhibited antibodies to the Flavivirus genus, one (6.2%) exhibited a monotypic reaction to Cacipacoré virus, one (6.2%) was associated with Mayaro virus, and one (6.2%) was positive for Oropouche virus. Conclusions: Based on the positive serology observed in the present study, it was possible to conclude that arboviruses circulate among free-living primates. The viruses in the areas studied might have been introduced by infected humans or by primates from endemic or enzootic areas. Studies of this nature, as well as effi cient and continuous surveillance programs, are needed to monitor viral activities in endemic and enzootic regions.

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Section: Discussionmentioning

confidence: 72%

Detection of arboviruses of public health interest in free-living New World primates (Sapajus spp.; Alouatta caraya) captured in Mato Grosso do Sul, Brazil

Batista

Andreotti

Almeida

et al. 2013

Rev. Soc. Bras. Med. Trop.

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“…Severe disease has been linked to these viruses in humans [7], [13], [43], [58], [59] and for WNV also in equines [60]. WNV and SLEV circulation in the Pantanal appears to be a recent phenomenon.…”

Section: Resultsmentioning

confidence: 99%

“…More recently, an outbreak of hemorrhagic manifestations was linked to Saint Louis encephalitis virus (SLEV) [4]. Sporadic human cases caused by other sylvatic flaviviruses, including Bussuquara virus (BSQV), Ilheus virus (ILHV) and Cacipacore virus (CPCV) have also been reported in Brazil [5], [6], [7]. Furthermore, yellow fever epizootics in howler monkeys were reported in 2008 and 2009.…”

Section: Introductionmentioning

confidence: 99%

Serological Evidence of Widespread Circulation of West Nile Virus and Other Flaviviruses in Equines of the Pantanal, Brazil

et al. 2014

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A recent study reported neutralizing antibodies to West Nile virus (WNV) in horses from four ranches of southern Pantanal. To extend that study, a serosurvey for WNV and 11 Brazilian flaviviruses was conducted with 760 equines, 238 sheep and 61 caimans from 17 local cattle ranches. Among the tested equines, 32 were collected from a ranch where a neurologic disorder outbreak had been recently reported. The sera were initially screened by using a blocking ELISA and then titrated by 90% plaque-reduction neutralization test (PRNT90) for 12 flaviviruses. Employing the criterion of 4-fold greater titer, 78 (10.3%) equines were seropositive for Ilheus virus, 59 (7.8%) for Saint Louis encephalitis virus, 24 (3.2%) for WNV, two (0.3%) for Cacipacore virus and one (0.1%) for Rocio virus. No serological evidence was found linking the neurological disease that affected local equines to WNV. All caimans and sheep were negative by blocking ELISA for flaviviruses. There were no seropositive equines for Bussuquara, Iguape, Yellow fever and all four Dengue virus serotypes. The detection of WNV-seropositive equines in ten ranches and ILHV and SLEV-seropositive equines in fourteen ranches of two different sub-regions of Pantanal is strong evidence of widespread circulation of these flaviviruses in the region.

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“…Injection into mice produces death [ 102 ]. A 33-year-old farmworker in the Brazilian state of Rondônia, Brazil, was admitted to intensive care with suspected leptospirosis and yellow fever; however, viral sequencing identifi ed CPCV as the cause of infection [ 103 ].…”

Section: Japanese Encephalitis Virus Complexmentioning

confidence: 99%

Flaviviruses: Yellow Fever, Japanese B, West Nile, and Others

Thomas

Martínez

Endy

2014

Viral Infections of Humans

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Notification of the first isolation of Cacipacore virus in a human in the State of Rondônia, Brazil

Cited by 25 publications

References 8 publications

Detection of arboviruses of public health interest in free-living New World primates (Sapajus spp.; Alouatta caraya) captured in Mato Grosso do Sul, Brazil

Detection of arboviruses of public health interest in free-living New World primates (Sapajus spp.; Alouatta caraya) captured in Mato Grosso do Sul, Brazil

Serological Evidence of Widespread Circulation of West Nile Virus and Other Flaviviruses in Equines of the Pantanal, Brazil

Flaviviruses: Yellow Fever, Japanese B, West Nile, and Others

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