Rede Brasileira de Atenção e Estudos na Co-infecção Trypanosoma cruzi/HIV e em outras condições de imunossupressão

Almeida, Eros Antônio de; Ramos, Alberto Novaes; Correia, Dalmo; Shikanai-Yasuda, Maria Aparecida

doi:10.1590/s0037-86822009000500025

Cited by 16 publications

(8 citation statements)

References 5 publications

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“…The data show an association of coinfection with early mortality, compared to deaths from Chagas disease only, as described in a previous study [10]. The magnitude of both AIDS and Chagas disease in Brazil as chronic conditions will probably increase the likelihood of occurrence of coinfection in the future [12]. …”

Section: Discussionsupporting

confidence: 77%

“…This indicates that Chagas reactivation in the central nervous system and myocardium is usually severe, often with fatal results [7]. Reactivation is suspected when the coinfected subject presents clinically acute Chagas disease or clinical decompensation of the chronic phase, organic impairment uncommon in Chagas disease, or pseudotumoral brain lesions [5, 7, 12]. In the case of absent or controlled reactivation, survival is directly related to the complications of Chagas disease and of HIV/AIDS infection.…”

Section: Discussionmentioning

confidence: 99%

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Mortality Related to Chagas Disease and HIV/AIDS Coinfection in Brazil

Martins-Melo

Ramos

Alencar

et al. 2012

Journal of Tropical Medicine

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Chagas disease in patients with HIV infection represents a potentially serious event with high case fatality rates. This study describes epidemiological and clinical aspects of deaths related to Chagas disease and HIV/AIDS coinfection in Brazil, 1999–2007. We performed a descriptive study based on mortality data from the nationwide Mortality Information System. Of a total of about 9 million deaths, Chagas disease and HIV/AIDS were mentioned in the same death certificate in 74 cases. AIDS was an underlying cause in 77.0% (57) and Chagas disease in 17.6% (13). Males (51.4%), white skin color (50%), age group 40–49 years (29.7%), and residents in the Southeast region (75.7%) were most common. Mean age at death was significantly lower in the coinfected (47.1 years [SD ± 14.6]), as compared to Chagas disease deaths (64.1 years [SD ± 14.7], P < 0.001). Considering the lack of data on morbidity related to Chagas disease and AIDS coinfection, the use of mortality data may be an appropriate sentinel approach to monitor the occurrence of this association. Due to the epidemiological transition in Brazil, chronic Chagas disease and HIV/AIDS coinfection will be further complicated and require the development of evidence-based preventive control measures.

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Section: Discussionsupporting

confidence: 77%

Section: Discussionmentioning

confidence: 99%

Mortality Related to Chagas Disease and HIV/AIDS Coinfection in Brazil

Martins-Melo

Ramos

Alencar

et al. 2012

Journal of Tropical Medicine

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“…Brazil, a country with a high prevalence of leishmaniasis, led scientific production on leishmaniasis in Latin America. This can be attributed to the number of researchers and development of the country’s scientific system, which has become the principal scientific reference for South America [20,29]. India, a country with a high prevalence of leishmaniasis, mainly in the state of Bihar [1,2,25,30], was the third country, and it led scientific production on leishmaniasis in Asia.…”

Section: Discussionmentioning

confidence: 99%

Bibliometric analysis of leishmaniasis research in Medline (1945-2010)

2013

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BackgroundPublications are often used as a measure of success of research work. Leishmaniasis is considered endemic in 98 countries, most of which are developing. This article describes a bibliometric review of the literature on leishmaniasis research indexed in PubMed during a 66-year period.MethodsMedline was used via the PubMed online service of the US National Library of Medicine. The search strategy was Leishmania [MeSH] or leishmaniasis [MeSH] from 1 January 1945 until 31 December 2010. Neither language nor document type restrictions were employed.ResultsA total of 20,780 references were retrieved. The number of publications increased steadily over time, with 3,380 publications from 1945-1980 to 8,267 from 2001-2010. Leishmaniasis documents were published in 1,846 scientific journals, and Transactions of the Royal Society of Tropical Medicine and Hygiene (4.9%) was the top one. The USA was the predominant country by considering the first author’s institutional address (16.8%), followed by Brazil (14.9%), and then India (9.0%), however Brazil leads the scientific output in 2001-2010 period (18.5%), followed by the USA (13.5%) and India (10%). The production ranking changed when the number of publications was normalised by population (Israel and Switzerland), by gross domestic product (Nepal and Tunisia), and by gross national income per capita (India and Ethiopia). For geographical area, Europe led (31.7%), followed by Latin America (24.5%).ConclusionsWe have found an increase in the number of publications in the field of leishmaniasis. The USA and Brazil led scientific production on leishmaniasis research.

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“…For this reason, a good reference is the afore-mentioned "Rede brasileira de atenção e estudos em co-infecção Trypanosoma cruzi/HIV (e outras condições de imunossupressão)", founded in 2006 in order to coordinate and organize the Brazilian healthcare network and to integrate established international groups into it. These efforts serve to promote synergies that contribute to an international network that improves care and strengthens the development of strategic studies in the area (ALMEIDA et al 2009;RAMOS JUNIOR et al 2010). In addition, it would be necessary to foster research in countries with high prevalence of the disease but where no notably productive authors have been identified, such as in Mexico, Bolivia, Guatemala, Ecuador, Honduras, El Salvador and Paraguay (RAMOS et al 2011).…”

Section: Discussionmentioning

confidence: 99%

Scientific authorships and collaboration network analysis on Chagas disease: papers indexed in PubMed (1940-2009)

González‐Alcaide

Park

Huamaní

et al. 2012

Rev. Inst. Med. trop. S. Paulo

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SUMMARYChagas disease is a chronic, tropical, parasitic disease, endemic throughout Latin America. The large-scale migration of populations has increased the geographic distribution of the disease and cases have been observed in many other countries around the world. To strengthen the critical mass of knowledge generated in different countries, it is essential to promote cooperative and translational research initiatives. We analyzed authorship of scientific documents on Chagas disease indexed in the Medline database from 1940 to 2009. Bibliometrics was used to analyze the evolution of collaboration patterns. A Social Network Analysis was carried out to identify the main research groups in the area by applying clustering methods. We then analyzed 13,989 papers produced by 21,350 authors. Collaboration among authors dramatically increased over the study period, reaching an average of 6.2 authors per paper in the last five-year period. Applying a threshold of collaboration of five or more papers signed in co-authorship, we identified 148 consolidated research groups made up of 1,750 authors. The Chagas disease network identified constitutes a "small world," characterized by a high degree of clustering and a notably high number of Brazilian researchers.

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Rede Brasileira de Atenção e Estudos na Co-infecção Trypanosoma cruzi/HIV e em outras condições de imunossupressão

Cited by 16 publications

References 5 publications

Mortality Related to Chagas Disease and HIV/AIDS Coinfection in Brazil

Mortality Related to Chagas Disease and HIV/AIDS Coinfection in Brazil

Bibliometric analysis of leishmaniasis research in Medline (1945-2010)

Scientific authorships and collaboration network analysis on Chagas disease: papers indexed in PubMed (1940-2009)

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