Nephrotic syndrome in hepatosplenic schistosomiasis mansoni

Lambertucci, José Roberto; Otoni, Alba; Reis, Marlene Antônia dos

doi:10.1590/s0037-86822007000400028

Cited by 6 publications

(4 citation statements)

References 2 publications

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“…There is also evidence of polyclonal B-lymphocytes activation [87], but it is not sufficient to induce the process of nephritis, so more recent studies suggest the participation of autoimmune mechanisms [88]. The most common pattern of glomerular disease in schistosomiasis is mesangial proliferative and membranoproliferative glomerulonephritis [89,90]. There are deposits of IgM, IgG, and C3 [91].…”

Section: Schistosomiasismentioning

confidence: 99%

Neglected Tropical Diseases with an Impact on Kidney Function

Silva¹,

Jereissati²,

Neri³

et al. 2018

Current Topics in Tropical Emerging Diseases and Travel Medicine

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Neglected tropical diseases are a group of infectious diseases caused by infectious and parasitic agents that occur in a large part of the world affecting millions of people and can complicate matters with serious organ damage. The kidneys can be affected in many of these diseases, including Chagas disease, dengue, leishmaniasis, leprosy, and schistosomiasis. In this chapter, we describe the mechanisms by which the kidneys are damaged in the setting of these diseases, the clinical manifestations, and the current available treatment options. We also describe the recent novel biomarkers that are under investigation for the early diagnosis of kidney injury in the course of these diseases and the future perspectives.

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Section: Schistosomiasismentioning

confidence: 99%

Neglected Tropical Diseases with an Impact on Kidney Function

Silva¹,

Jereissati²,

Neri³

et al. 2018

Current Topics in Tropical Emerging Diseases and Travel Medicine

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“…In patients with hepatosplenic schistosomiasis, the most frequently found glomerulopathy is mesangial proliferative and membranoproliferative glomerulonephritis [22,23] (Figure 4). The mesangium is the most affected glomerular segment in schistosomiasis.…”

Section: Histopathologymentioning

confidence: 99%

Schistosomiasis-associated kidney disease: A review

Silva

Duarte

Barros

et al. 2013

Asian Pacific Journal of Tropical Disease

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“…5 To our knowledge, there is no recent field work addressing this issue. Even after mass chemotherapy severe conditions, including schistosomal glomerulopathy, have been reported 6,7 ; the high prevalence of glomerulopathy in schistosomiasis and the early detection of renal involvement may interrupt or delay the progression of glomerulopathy to end stage renal disease. 8 The chemokine profiles for the early diagnoses of the diseases that evolve with proteinuria and glomerular injury have already been described.…”

Section: Introductionmentioning

confidence: 99%

Chemokine Profile in the Sera and Urine of Patients with Schistosomal Glomerulopathy

Otoni

Teixeira

Voieta

et al. 2014

The American Journal of Tropical Medicine and Hygiene

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Abstract. We investigated the serum and urine chemokine levels of patients with schistosomal mansoni glomerulonephritis. This cross-sectional study was conducted in the Southeast of Brazil. Overall, 160 subjects were enrolled and divided into five groups: 1) hepatosplenic schistosomiasis with renal disease (N = 12); 2) hepatosplenic schistosomiasis without renal disease (N = 68); 3) hepatointestinal schistosomiasis (N = 27); 4) glomerulopathy caused by other diseases (N = 22); and 5) healthy controls (N = 31). The patients with microalbuminuria 30 mg in 24 hours were considered to have renal disease. The sera and urine chemokines CCL2, CCL3, CCL5, CCL11, and CXCL8 were measured using an enzyme-linked immunosorbent assay test. A similar profile was observed between the patients with schistosomal glomerulopathy and the patients with glomerulopathy caused by other diseases, with the exception of serum CCL2 634.3 pg/mL. In cases with sera CCL2 634.3 pg/mL, the diagnosis of schistosomal glomerulopathy should be considered.

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Nephrotic syndrome in hepatosplenic schistosomiasis mansoni

Cited by 6 publications

References 2 publications

Neglected Tropical Diseases with an Impact on Kidney Function

Neglected Tropical Diseases with an Impact on Kidney Function

Schistosomiasis-associated kidney disease: A review

Chemokine Profile in the Sera and Urine of Patients with Schistosomal Glomerulopathy

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