Mycetoma fungal infection: multiple organisms as colonizers or pathogens?

Pilsczek, Florian H.; Augenbraun, Michael

doi:10.1590/s0037-86822007000400017

Cited by 20 publications

(17 citation statements)

References 16 publications

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“…[2628] The study of discharged granules crushed on the slide and stained with special stains, most notably lactophenol blue, particularly allows differentiation between the thin filaments of actinomycetoma and the thicker hyphae of eumycetoma.…”

Section: Laboratory Diagnosismentioning

confidence: 99%

Mycetoma: An update

et al. 2017

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Mycetoma is a localized chronic, suppurative, and deforming granulomatous infection seen in tropical and subtropical areas. It is a disorder of subcutaneous tissue, skin and bones, mainly of feet, characterized by a triad of localized swelling, underlying sinus tracts, and production of grains or granules. Etiological classification divides it into eumycetoma caused by fungus, and actinomycetoma caused by bacteria. Since the treatment of these two etiologies is entirely different, a definite diagnosis after histopathological and microbiological examination is mandatory, though difficult. Serological test exists but is not so reliable; however, molecular techniques to identify relevant antigens have shown promise. The disease is notoriously difficult to treat. Eumycetoma may be unresponsive to standard antifungal therapy. Actinomycetoma responds to antibiotic therapy, but prolonged treatment is necessary. This review focuses on the etiopathogenesis, clinical features, laboratory diagnosis, and treatment of mycetoma.

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Section: Laboratory Diagnosismentioning

confidence: 99%

Mycetoma: An update

et al. 2017

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“…In eumycotic mycetoma, there may be multiple punched out lytic lesions in bones. Actinomycotic mycetoma is characterized by both osteolytic and osteosclerotic lesions [6,7,10].…”

Section: Discussionmentioning

confidence: 99%

“…The granules of actinomycetoma consists of fine branching filaments, only about 1um thick are gram positive, whereas the grains of eumycetoma are gram negative [10]. Eumycotic grains are composed of 4-5μm thick septate hyphae and are demonstrated by PAS (periodic acid-Schiff) and GMS (Gomori methenamine silver) stains [13].…”

Section: Discussionmentioning

confidence: 99%

Eumycetoma on histopathology presenting at unusual site: A rare entity.

Shah

Karki

Rai

et al. 2018

Int Jour of Biomed Res

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Mycetoma, an uncommon chronic infection of skin and subcutaneous tissues; commonly seen in tropical and subtropical countries. It is caused by true mycetes named eumycetoma and filamentous bacteria belonging to group actinomycetes. The incidence is more common in agricultural workers walking in bare foot. Foot is most commonly affected. Other less commonly affected sites includes hand, knee, chest and head and neck region. Both forms of mycetoma present as a progressive, subcutaneous multiple nodular swelling with discharging sinuses containing black colour granules. The treatment of these two etiologies is entirely different, a definite diagnosis after histopathological examination is mandatory. We here by present a case of eumycetoma affecting knee joint.

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“…Regarding the prevalence of subcutaneous mycoses, several cases of mycetoma due to Nocardia species, Acremonium sp and Madurella mycetomatis have been reported (27)(28)(29)(30). Bansal and Prabhakar (31) reported 31 histologically confirmed cases of chromoblastomycosis with positive cultures of Fonsecea pedrosoi in 16 of them.…”

Section: Discussionmentioning

confidence: 99%