Características clinicoepidemiológicas de um grupo de mulheres com HIV/AIDS em Salvador-Bahia

Toxoplasmosis is considered one of the opportunistic infections for individuals with the Acquired Immunodeficiency Syndrome (AIDS), and is also a major cause of morbidity and mortality. The aim of this study was to evaluate the prevalence of neurotoxoplasmosis, ocular toxoplasmosis and antibodies for Toxoplasma gondii in HIV-positive patients attending the SAE (Specialized Assistance Service for HIV/AIDS), as well as to associate their serological profile with epidemiological and clinical data. A total of 250 patients participated in the study from December, 2009 to November, 2010. Serological analysis was performed using the indirect immunofluorescent technique; epidemiological data were gathered by a questionnaire, and clinical history was based on the analysis of medical charts. Prevalence of seropositivity was 80%, with history of neurotoxoplasmosis in 4.8% and of ocular toxoplasmosis in 1.6% of the patients. The Highly Active Antiretroviral Treatment (HAART) was not used by 32% of the patients, 18.4% of the patients had CD4+ T- lymphocyte count less than 200 cells/mm³ and 96.8% of them were not aware of the modes of disease transmission. These findings led us to conclude that the study population is at high risk of clinical toxoplasmosis, because of both reactivation of infection in the seropositive patients who do not make a regular use of HAART, and primo-infection in seronegative patients worsened by an unawareness of the modes of infection reported in this study.

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“…Seroprevalence in immunosuppressed individuals was similar to that reported by other studies in Brazil: Pará (82.9%) 13 and Bahia (77.3%) 23 .…”

Section: Discussionsupporting

confidence: 89%

Evaluation of seroepidemiological toxoplasmosis in HIV/AIDS patients in the south of Brazil

Xavier

Cademartori

Filho

et al. 2013

Rev. Inst. Med. trop. S. Paulo

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“…The rate between men and women was 2.5:1 (M:W), which is in agreement with the current trend of epidemic dissemination among women 24 . The low M:W rate obtained can be partially explained by sexual exposure as the most probable form of HIV transmission, with prominence of heterosexual behavior.…”

Section: Discussionsupporting

confidence: 88%

Clinical and epidemiological analysis of patients with HIV/AIDS admitted to a reference hospital in the northeast region of Brazil

Soares

Filho

Carvalho

et al. 2008

Rev. Inst. Med. trop. S. Paulo

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SUMMARYThe AIDS epidemic has become a worldwide phenomenon of enormous magnitude and extension, deeply transforming medical practices and public health initiatives. This retrospective survey aimed to analyze clinical and epidemiological characteristics of patients with HIV/AIDS admitted to the Institute of Tropical Diseases Natan Portella, Teresina, Piauí, Brazil, from January, 2001 through December, 2004. Of the 828 patients, 43% were from other states and 71.3% were men. Average patient age was 35.4 ± 11.5 years-old and 85.5% were illiterate or had primary education. The main form of exposure to HIV was heterosexual behavior (54.1%), while injectable drug use was confirmed by only 2.7% of registered cases. The most frequent infectious complications were candidiasis (42.4%) and pneumocystosis (22.2%). Sixty-eight cases (8.2%) of visceral leishmaniasis were registered. Using multivariate analysis, individuals aged over 40 years-old, patients with active tuberculosis, Pneumocystis carinii pneumonia and central nervous system cryptococcosis showed increased risk of death. In this study, young male adults with low educational levels predominated and the most frequent opportunistic infections were candidiasis and pneumocystosis.

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“…In this study, we found that HIV-positive pregnant and nonpregnant women from Northeast of Brazil had significantly lower education, income employment, and social status and higher number of children than those of women without HIV infection. These findings of impoverishment of the AIDS epidemic has been previously reported in others studies in Brazil [28][29][30][31] . In a study of HIV-infected women by Friedman et al, in 2011, an inverse correlation was observed between education level and pregnancy, and the risk of pregnancy was 75% higher among women with up to three years of education than that in women with nine years or more of education 29 .…”

Section: Discussionsupporting

confidence: 88%

Social conditions and immune response in human immunodeficiency virus-seropositive pregnant women: a cross-sectional study in Brazil

Sampaio

Vasconcelos

Morais

et al. 2018

Rev. Soc. Bras. Med. Trop.

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Características clinicoepidemiológicas de um grupo de mulheres com HIV/AIDS em Salvador-Bahia

Cited by 8 publications

References 13 publications

Evaluation of seroepidemiological toxoplasmosis in HIV/AIDS patients in the south of Brazil

Evaluation of seroepidemiological toxoplasmosis in HIV/AIDS patients in the south of Brazil

Clinical and epidemiological analysis of patients with HIV/AIDS admitted to a reference hospital in the northeast region of Brazil

Social conditions and immune response in human immunodeficiency virus-seropositive pregnant women: a cross-sectional study in Brazil

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