Intradermorreação de Montenegro após sucessivas repetições do teste em Porteirinha, MG

Abstract

With the purpose of evaluating the response of sequential applications of Montenegro intradermoreaction (IDRM), we have repeated four times the test in the inhabitants of an endemic area for kala-azar, that resulted negative 3-4 years ago. Firstly, we have repeated three IDRM in those who remained negative, with a 60-day interval among them. In the second stage, we have performed a last reaction in all participants of the study. From the total of 49 individuals with prior negative IDRM, 19 (38.8%) have positivated the test in some of the times, 17 (34.7%) have given up the study and 13 (26.5%) remained with a negative result in all the applications. In the second stage, the repetition of IDRM has shown that from the 14 positive in some of the tests, 8 remained like this and 6 have become negative. Our results confirm the possibility of late hypersensitivity induction in some individuals as a consequence of IDRM application.

Antileishmania Immunological Tests for Asymptomatic Subjects Living in a Visceral Leishmaniasis-Endemic Area in Brazil

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“…13,14 Clinical reassessment 3-4 years after the first evaluation revealed that none of the subjects who tested positive developed classical VL. This result would be expected for subjects with a positive MST.…”

Epidemiologia da leishmaniose tegumentar americana no Estado do Acre, Amazônia brasileira

“…Esse teste constitui-se, portanto, em excelente auxiliar do diagnóstico clínico da doença, mas não como única ferramenta para este fim. Logo, tem sua devida importância em certos contextos epidemiológicos 26 .…”

Especificidad de la prueba intradérmica de Montenegro en pacientes infectados por Trypanosoma cruzi procedentes de diferentes regiones del Perú

“…Por otro lado, al ser la leishmanina un antígeno extracto proteíco soluble, es de esperar que compartan epítopes en común, ya que, como se conoce, Leishmania y Trypanosoma, son trypanosomatídeos estrechamente relacionados. Además, es posible que estos pacientes hayan sido evaluados previamente con la leishmanina dado que provienen de zonas endémicas para Leishmania, y ello podría haber inducido su respuesta cutánea, tal como lo sugieren los estudios que evaluaron aplicaciones secuenciales de la leishmanina (10,11) .…”