Avaliação do impacto das ações de controle vetorial da doença de Chagas através do inquérito sorológico em Mambaí/Buritinópolis, Goiás

Peñaranda-Carrillo, Rosaura; Moreira, Eliana Furtado; Silveira, Antônio Carlos; Leite, João; Vinhaes, Márcio Costa; Castro, Cleudson; Macêdo, Vanize

doi:10.1590/s0037-86822002000400009

Cited by 6 publications

(2 citation statements)

References 8 publications

(1 reference statement)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Repeated serodiagnosis in endemic rural areas over many years showed some departures from the expected pattern of lifelong seroreactivity to T. cruzi in humans (ref. 27 and this study) but hardly ever in dogs (16,22). Although improved, highly specific serological tests are necessary to assess the impact of field interventions and treatment in humans, the use of dogs as disease sentinels and bug-related indices demonstrated large differences in domestic transmission between sustained and pulsedcontrol areas.…”

Section: Discussionmentioning

confidence: 67%

Sustainable vector control and management of Chagas disease in the Gran Chaco, Argentina

Gürtler

Kitron

Cecere

et al. 2007

Proc. Natl. Acad. Sci. U.S.A.

228

286

View full text Add to dashboard Cite

Chagas disease remains a serious obstacle to health and economic development in Latin America, especially for the rural poor. We report the long-term effects of interventions in rural villages in northern Argentina during 1984 -2006. Two community-wide campaigns of residual insecticide spraying immediately and strongly reduced domestic infestation and infection with Trypanosoma cruzi in Triatoma infestans bugs and dogs and more gradually reduced the seroprevalence of children <15 years of age. Because no effective surveillance and control actions followed the first campaign in 1985, transmission resurged in 2-3 years. Renewed interventions in 1992 followed by sustained, supervised, community-based vector control largely suppressed the reestablishment of domestic bug colonies and finally led to the interruption of local human T. cruzi transmission. Human incidence of infection was nearly an order of magnitude higher in peripheral rural areas under pulsed, unsupervised, community-based interventions, where human transmission became apparent in 2000. The sustained, supervised, community-based strategy nearly interrupted domestic transmission to dogs but did not eliminate T. infestans despite the absence of pyrethroid-insecticide resistance. T. infestans persisted in part because of the lack of major changes in housing construction and quality. Sustained community participation grew out of establishing a trusted relationship with the affected communities and the local schools. The process included health promotion and community mobilization, motivation, and supervision in close cooperation with locally nominated leaders. community participation ͉ deltamethrin ͉ pyrethroids ͉ Triatoma infestans ͉ Trypanosoma cruzi

show abstract

Section: Discussionmentioning

confidence: 67%

Sustainable vector control and management of Chagas disease in the Gran Chaco, Argentina

Gürtler

Kitron

Cecere

et al. 2007

Proc. Natl. Acad. Sci. U.S.A.

228

286

View full text Add to dashboard Cite

show abstract

“…Finally, for four among these 57 T. cruzi -confirmed seropositive children, the mothers were seronegative, and one child had received a prior blood transfusion. This information was documented to update the findings that had been gathered on the extent and the risk of the transmission of Chagas disease in Paraguay in 2001 ( Peñaranda-Carrillo et al 2002 , OPS 2004 ).…”

mentioning

confidence: 99%

Chagas disease: national survey of seroprevalence in children under five years of age conducted in 2008

Russomando

Cousiño

Sánchez

et al. 2017

Mem. Inst. Oswaldo Cruz

View full text Add to dashboard Cite

BACKGROUND Since the early 1990s, programs to control Chagas disease in South America have focused on eradicating domiciliary Triatoma infestans, the main vector. Seroprevalence studies of the chagasic infection are included as part of the vector control programs; they are essential to assess the impact of vector control measures and to monitor the prevention of vector transmission.OBJECTIVE To assess the interruption of domiciliary vector transmission of Chagas disease by T. infestans in Paraguay by evaluating the current state of transmission in rural areas.METHODS A survey of seroprevalence of Chagas disease was carried out in a representative sample group of Paraguayans aged one to five years living in rural areas of Paraguay in 2008. Blood samples collected on filter paper from 12,776 children were tested using an enzyme-linked immunosorbent assay. Children whose serology was positive or undetermined (n = 41) were recalled to donate a whole blood sample for retesting. Their homes were inspected for current triatomine infestation. Blood samples from their respective mothers were also collected and tested to check possible transmission of the disease by a congenital route.FINDINGS A seroprevalence rate of 0.24% for Trypanosoma cruzi infection was detected in children under five years of age among the country’s rural population. Our findings indicate that T. cruzi was transmitted to these children vertically. The total number of infected children, aged one to five years living in these departments, was estimated at 1,691 cases with an annual incidence of congenital transmission of 338 cases per year.MAIN CONCLUSION We determined the impact of vector control in the transmission of T. cruzi, following uninterrupted vector control measures employed since 1999 in contiguous T. infestans-endemic areas of Paraguay, and this allowed us to estimate the degree of risk of congenital transmission in the country.

show abstract

Chagas Disease: An Unknown and Neglected Disease

et al. 2020

View full text Add to dashboard Cite

Avaliação do impacto das ações de controle vetorial da doença de Chagas através do inquérito sorológico em Mambaí/Buritinópolis, Goiás

Cited by 6 publications

References 8 publications

Sustainable vector control and management of Chagas disease in the Gran Chaco, Argentina

Sustainable vector control and management of Chagas disease in the Gran Chaco, Argentina

Chagas disease: national survey of seroprevalence in children under five years of age conducted in 2008

Chagas Disease: An Unknown and Neglected Disease

Contact Info

Product

Resources

About