Soroprevalência de anticorpos contra o sarampo de uma determinada população infantil de Botucatu, SP

Abstract

A study of the seroprevalence of measles antibodies was conducted in a population of children residing in Botucatu, SP, in order to asses their immunological status whether induced by natural infection or by vaccination. A total of 101 children were studied, all of which had been vaccinated against measles. The laboratory tests used to determine the presence of antibodies in the collected blood samples were hemagglutination inhibition (HI) and immunoenzymatic assay (ELISA). HI results showed that 92.1% of the samples presented antibodies against measles. Samples with titers <1:4 when studied by HI were retested by ELISA in the same laboratory and only two continued to be negative for measles antibodies. Thus, measles antibodies were present in 98% of the serum samples from the children studied.

Measles, rubella, mumps and Toxoplasma gondii antibodies in saliva of vaccinated students of schools and universities in São Paulo City, Brazil

“… 21 It is known that the measles vaccination failure rate ranges from two to 10%, and it is an important issue in the epidemiology of the disease, since the transmission could only occur due to failures in childhood vaccine coverage. 22 Recent studies have shown that children are the primary targets for measles and, in this non-invasive technical context for diagnosis, saliva can be a very useful tool in early detection of measles. The results confirm that both serological and molecular assays of oral fluid are suitable for routine use.…”