Hanseníase virchowiana em cardiopata chagásico: relato de necropsia

Lima, Marcus Aurelho de; Rodrigues, Virmondés; Silva‐Vergara, Mario León; Nomelini, Maria Betânia; Paim, Neiva Pereira; Santos, Taciana Arruda Modesto dos; Santos, Vitorino Modesto dos

doi:10.1590/s0037-86821998000400008

Cited by 2 publications

(2 citation statements)

References 6 publications

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“…inside heart nerve filaments. 14 One of the challenges in management of the patient was to exclude myocarditis caused by reactivation of T. cruzi as the cause of the decompensation of the chronic cardiopathy. Reactivation could be caused by either immunosuppression secondary to M .…”

Section: Discussionmentioning

confidence: 99%

A Patient with Erythema Nodosus Leprosum and Chagas Cardiopathy: Challenges in Patient Management and Review of the Literature

Trindade¹,

Carvalho²,

Belfort³

et al. 2011

The American Society of Tropical Medicine and Hygiene

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Abstract. We report a patient with severe multi-bacillary leprosy complicated by recurrent episodes of erythema nodosum necrotisans that required thalidomide and/or corticosteroids during follow-up. Although the patient was from an area to which Chagas disease is endemic, this diagnosis was initially missed and was only investigated when heart failure developed in the patient. The difficulties of managing erythema nodosum necrotisans and heart failure concomitantly and those involved in excluding the diagnosis of acute myocarditis caused by reactivation of Chagas disease secondary to the immunosuppressive regimen are discussed. Other potential causes for the heart failure and possible interactions between the two diseases and their treatments are discussed. We also reviewed the literature for the association between leprosy and Chagas disease, both of which are highly endemic in Brazil. This case emphasizes the importance of searching for subclinical co-infections in leprosy patients because reactions frequently develop during specific treatment in these patients, and these reactions require prolonged therapy with immunosuppressive drugs.

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Section: Discussionmentioning

confidence: 99%

A Patient with Erythema Nodosus Leprosum and Chagas Cardiopathy: Challenges in Patient Management and Review of the Literature

Trindade¹,

Carvalho²,

Belfort³

et al. 2011

The American Society of Tropical Medicine and Hygiene

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“…En estudios electrocardiográficos hechos en pacientes con lepra y mal de Chagas se observó que las anomalías se presentaban casi con la misma frecuencia tanto en pacientes coinfectados como en pacientes con una u otra enfermedad (21). Los pacientes reportados con ambas afecciones presentaban miocardiopatía chagásica (22). No pudimos encontrar en la literatura disponible (PUBMED y Google Scholar) ningún caso de asociación entre lepra y megaesófago chagásico como nuestro reporte.…”

Section: Discusionunclassified

Penile Lepromatous Leprosy in a Patient With Chagas DISEASE.A Case Report

Zarza¹,

Hong²,

Park³

et al. 2016

An. Fac. Cienc. Méd. (Asunción)

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RESUMENSe presenta el caso de un paciente masculino de 52 años con fimosis secundaria a una masa pseudotumoral prepucial. El paciente presentaba una historia de enfermedad de Hansen con afectación de piel, laringe y bronquios. Previa a la circuncisión, el examen físico revelaba, además de las alteraciones lepromatosas, un mega esófago secundario a estenosis en la porción distal. El análisis laboratorial mediante la técnica de ELISA dio positivo para Trypanosoma cruzi, patógeno responsable de la enfermedad de Chagas. Sólo pudimos encontrar un caso previo reportado de lepra lepromatosa con afectación prepucial. La coexistencia de lepra y miocardiopatía chagásica es inusual pero bien conocida por casos reportados en Brasil e India. Sin embargo, de acuerdo a nuestros conocimientos, éste es el primer caso reportado de una asociación entre lepra lepromatosa y mega esófago chagásico en un paciente con fimosis.Palabras Clave: Lepra Lepromatosa, Enfermedad de Chagas, Fimosis.

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Hanseníase virchowiana em cardiopata chagásico: relato de necropsia

Cited by 2 publications

References 6 publications

A Patient with Erythema Nodosus Leprosum and Chagas Cardiopathy: Challenges in Patient Management and Review of the Literature

A Patient with Erythema Nodosus Leprosum and Chagas Cardiopathy: Challenges in Patient Management and Review of the Literature

Penile Lepromatous Leprosy in a Patient With Chagas DISEASE.A Case Report

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