Estudo comparativo entre o estibogluconato de sódio BP88® (Shandong Xinhua - China) e o antimoniato de meglumina (Rhodia - Brasil) no tratamento da forma cutânea de leishmaniose tegumentar americana, na área endêmica de Corte de Pedra, Bahia, Brasil

Saldanha, Ana Cristina R.

doi:10.1590/s0037-86821998000200013

Rev. Soc. Bras. Med. Trop.

1998

DOI: 10.1590/s0037-86821998000200013

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Estudo comparativo entre o estibogluconato de sódio BP88® (Shandong Xinhua - China) e o antimoniato de meglumina (Rhodia - Brasil) no tratamento da forma cutânea de leishmaniose tegumentar americana, na área endêmica de Corte de Pedra, Bahia, Brasil

Ana Cristina R. Saldanha¹

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2003

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Óbito durante tratamento da leishmaniose tegumentar americana com stibogluconato de sódio bp 88® (shandong xinhua)

Costa

Garcia

Rebêlo

et al. 2003

Rev. Soc. Bras. Med. Trop.

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The authors report the occurrence of a fatal case in patient with cutaneous leishmaniasis in the municipality of Caxias, MA. Male patient, 22 years old, road sweeper, presented with an ulcer in left leg, diagnosed as cutaneous leishmaniasis and treated with sodium stibogluconate BP88 (Sb+5) (Shandong Xinhua) at a dose of 10mg/Sb+5/kg/day/20 days. After dose three he presented arthralgia, myalgia, nausea and weakness. During the therapy there was an aggravation of the symptoms with abdominal pain and irradiation into the thorax. After dose seven he presented a picture of associated dyspnea and thoracic pain of mild intensity. At dose nine there was further worsening of the picture, nevertheless the therapy was continued up to dose 11, when the patient's state deteriorated to such an extent that he was hospitalized in the intensive care unit. Exams: erythrocytes, 4.4 million; hemoglobin, 10.6%; hematocrits, 35%; white blood cells 26,400, basophiles and myelocytes (0); segmented leukocytes, 59%; lymphocytes 30%; monocytes 2%; platelets (normal); glucose, 42mg%; urea, 73mg%; creatinine, 2.4mg%; and ECG (blockade of right branch). The patient died from cardiorespiratory insufficiency. The current report underscores the need to clarify health workers regarding the use of Sb+5 and also to remind the Health Ministry to verify the quality and origin when acquiring new products.

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Óbito durante tratamento da leishmaniose tegumentar americana com stibogluconato de sódio bp 88® (shandong xinhua)

Costa

Garcia

Rebêlo

et al. 2003

Rev. Soc. Bras. Med. Trop.

View full text Add to dashboard Cite

show abstract

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Estudo comparativo entre o estibogluconato de sódio BP88® (Shandong Xinhua - China) e o antimoniato de meglumina (Rhodia - Brasil) no tratamento da forma cutânea de leishmaniose tegumentar americana, na área endêmica de Corte de Pedra, Bahia, Brasil

Cited by 1 publication

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Óbito durante tratamento da leishmaniose tegumentar americana com stibogluconato de sódio bp 88® (shandong xinhua)

Óbito durante tratamento da leishmaniose tegumentar americana com stibogluconato de sódio bp 88® (shandong xinhua)

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