Chronic malaria and Brazil

Marsden, Philip D.

doi:10.1590/s0037-86821990000400001

Rev. Soc. Bras. Med. Trop.

1990

DOI: 10.1590/s0037-86821990000400001

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Chronic malaria and Brazil

Philip D. Marsden

Abstract: R e vista d a S o cied a d e B ra sileira de M ed icin a T ropical 2 3 (4 ): 1 9 3 -1 9 6 , out-dez, 1 9 9 0 P h ilip D a v is M a rsd en

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Cited by 3 publications

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Letter from Brasilia: Chronic malaria syndromes

Marsden¹

1993

BMJ

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Related disciplinesMost medical specialties have links with other medical and paramedical disciplines. Details of the services provided by such disciplines can be mentioned in the handbook. We find that such information is usefully gathered by visiting the departments, which can be included in any induction course. The handbook should contain details of the referral information required by the particular professionals concerned. When describing social work and appliances it might

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Letter from Brasilia: Chronic malaria syndromes

Marsden¹

1993

BMJ

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Reduction of spleen size in a child with Hyperreactive Malarious Splenomegaly (HMS) treated outside the Brazilian endemic area of malaria with only one course of quinine

Muniz‐Junqueira¹,

Moraes²,

Marsden³

1992

Rev. Soc. Bras. Med. Trop.

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We report the clinical picture, treatment and evolution of a child with hyperreactive malarious splenomegaly treated outside the endemic area of malaria. The patient presented gross splenomegaly, proceeded from an area where malaria is endemic, showed increased immunoglobulins levels, high antimalarial antibody titres and hepatic sinusoidal lymphocytosis. The child did not return to an area where malaria is endemic and showed a favorable response to only one course of quinine. The response of this patient to limited antimalarial therapy suggests the importance of reinfection with malaria in the development and maintenance of this syndrome.

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Importance of clinical and laboratory profiles for the differential diagnosis of malaria and acute viral hepatitis

et al. 2003

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Objectives: To establish clinical and diagnostic findings of malaria and acute viral hepatitis in children, stressing similarities and differences, so as to enhance the sensitivity of early malaria diagnosis in childhood. Methods: Two groups were studied, each including 30 children between 2 and 10 years of age. The patients presented either primary malaria infection or acute viral hepatitis, confirmed by thick blood film and tests for markers of viral hepatitis A and B. The patients were submitted to the following evaluations: erythrocyte, leucocyte and platelet counts, hemoglobin and hematocrit dosage, hepatic enzymes, urea, creatinine and bilirubin dosage. Clinical and laboratory findings were described for both groups and compared. Individuals with alterations on the physical exam in both groups were compared using Fisher's exact test. Results: Baseline clinical findings were the same in all patients: fever, headache, digestive problems and dark urine. One half of malaria patients did not present the classical malaria signs, but all of them presented fever, differently from patients with hepatitis. In malaria patients, anemia and thrombocytopenia were significantly more frequent than in hepatitis patients. A remarkable increase of bilirubin and hepatic enzyme levels was found in hepatitis patients. Conclusions: A detailed physical examination and a thorough evaluation of non-specific laboratory tests are sufficient to allow the presumptive diagnosis of both malaria and viral hepatitis, and to reinforce the early diagnosis and treatment of malaria.

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Chronic malaria and Brazil

Abstract: R e vista d a S o cied a d e B ra sileira de M ed icin a T ropical 2 3 (4 ): 1 9 3 -1 9 6 , out-dez, 1 9 9 0 P h ilip D a v is M a rsd en

Cited by 3 publications

References 12 publications

Letter from Brasilia: Chronic malaria syndromes

Letter from Brasilia: Chronic malaria syndromes

Reduction of spleen size in a child with Hyperreactive Malarious Splenomegaly (HMS) treated outside the Brazilian endemic area of malaria with only one course of quinine

Importance of clinical and laboratory profiles for the differential diagnosis of malaria and acute viral hepatitis

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