Ultrastructural alterations of intracellular stages and effects on blood forms of Trypanosoma cruzi induced in vivo by 2-amino-5-(1-methyil-5-nitro-2-imidazolyl)-1,3,4 - Thiadiazole

Abstract

Thaisa de Alm eida M aria2, Leny de Sousa Filardi3 and Zigm an Brener4An electron microscopy study shows that the administration o f a single dose (500 mg/kg, p.o.) o f 2-amino-5-(l-methyl-5-nitro-2-imidazolyl)-l, 3, 4-thiadiazole

Ultrastructural alterations of intracellular stages and effects on blood forms of Trypanosoma cruzi induced in vivo by 2-amino-5-(1-methyil-5-nitro-2-imidazolyl)-1,3,4 - Thiadiazole

“…Ultrastructuralalterations o f intracellularstages andeffects on bloodforms o f Trypanosoma cruzi induced in vivo by 2-amino-5-(l-methyl-5-nitro-2-imidazolyl)-l, 3, 4-thiadiazole. Revista da Sociedade Brasileira de Medicina Tropical 17: 89-93, Abr-Jun, 1984 ( Fig. 1) a number of ultrastructural alterations were observed as soon as 6 hours after drug administration in the treated animais.…”