Enterococcus gallinarum meningitis in an immunocompetent host: a case report

Antonello, Vicente Sperb; Zenkner, Francis de Moura; França, Josiane

doi:10.1590/s0036-46652010000200009

Cited by 10 publications

(5 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…faecium accounts for approximately 90% of enterococcal meningitis cases. CNS infections caused by E. gallinarum are rare but have been reported more often in recent years 11–14 . Consistent with other reports, E. faecalis and E. faecium were common, whereas E. gallinarum was isolated in only three patients in our study.…”

Section: Discussionsupporting

confidence: 92%

Experience with enterococcal meningitis/ventriculitis in children

Çay

Alabaz

Gündeşlioglu

et al. 2023

Pediatrics International

View full text Add to dashboard Cite

BackgroundEnterococcal infections are increasingly common in hospitalized patients. Enterococcal meningitis/ventriculitis (EMV) is an extremely rare condition of enterococcal infections, occurring particularly in children. This study investigated the clinical and microbiological characteristics, predisposing factors, and prognosis in pediatric patients with EMV.MethodsPediatric patients (<18 years) diagnosed with EMV were retrospectively evaluated over 10 years.ResultsThe study included a total of 25 isolates from 24 patients, median age 23 months (range: 1–136 months). The most common symptoms included vomiting, fever, and headache, with hydrocephalus shunt and preterm birth being the two most common conditions. Commonly associated infections, with central nervous system (CNS) devices as a predisposing factor, were due to external ventricular drainage and ventriculoperitoneal shunts. Two patients with spontaneous meningitis were preterm infant. Of the isolates, 44% were Enterococcus faecalis, 44% E. faecium, and 12% E. gallinarum. Five (20%) isolates were vancomycin resistant. Twelve patients were resistant to anti‐enterococcal antibiotics, including ampicillin, ciprofloxacin, imipenem, teicoplanin, gentamicin, and linezolid (40%, 20%, 8%, 8%, 4%, and 4%, respectively). Enterococcus faecium was more resistant to ampicillin, ciprofloxacin, teicoplanin, and vancomycin than E. faecalis. The median treatment duration was 17 days (interquartile range: 14–26 days).The mortality rate was 8.3% (2/24; both associated with vancomycin resistance).ConclusionsNeurosurgical conditions are the most common predisposing factors for EMV. Preterm birth is an important predisposing factor in children. Because EMV is nonspecific in clinical findings, it should be considered when there is an underlying CNS disorder and empirical treatment should begin in this direction.

show abstract

Section: Discussionsupporting

confidence: 92%

Experience with enterococcal meningitis/ventriculitis in children

Çay

Alabaz

Gündeşlioglu

et al. 2023

Pediatrics International

View full text Add to dashboard Cite

show abstract

“…While the occurrence of E faecalis meningitis and E faecium meningitis accounts for about 90% of enterococcus meningitis. Only 6 EGM cases were reported (details shown in Table 1 ), [ 2 ] including 4 cases secondary to neurosurgery, 1 case secondary to lumbar puncture, and 1 alcoholism patient, [ 3 – 5 ] and the youngest patient was 12 years old. We reported a case of a 9-day-old baby with neonatal EGM.…”

Section: Discussionmentioning

confidence: 99%

The first case report of Enterococcus gallinarum meningitis in neonate

Li¹,

Fan²,

Lin³

et al. 2018

Medicine

View full text Add to dashboard Cite

Rationale:Enterococcus gallinarum meningitis (EGM) is rarely found in normal adults and even rarer in children. To our knowledge, EGM in neonate has not been reported previously.Patients concerns:Here we reported the first case of EGM in neonate. Prolonged fever was the only manifestation for the case after admission.Diagnoses:Cerebrospinal fluid cultures showed that the isolate was Enterococcus gallinarum and sensitive to linezolid.Interventions:Ceftriaxone, beta lactam type, and vancomycin were used respectively, but not effective.Outcomes:The temperature went down to normal after linezolid was used and the baby was discharged in good condition in the end.Lessons:This case indicated that EGM could also occur in neonate and fever could be the only obvious manifestation. Thus, the effective antibiotics and adequate duration are very important and linezolid is a potential good choice, especially for vancomycin-resistant patients.

show abstract

“…E. faecalis and E. faecium are the two species most frequently isolated during the course of meningitis, whereas E. gallinarum is extremely rare. A PubMed (http://www.ncbi.nlm.nih.gov/pubmed?term=Enteroc occus%20gallinarum%20meningitis) search identified only five cases of E. gallinarum meningitis reported in the literature [6][7][8][9], summarized along with this study in Table 1. The low incidence of E. gallinarum meningitis may be attributed to an underestimation of the cases due to misidentification.…”

Section: Discussionmentioning

confidence: 99%

Enterococcus gallinarum meningitis: a case report and literature review

Khan

Elshafi

2011

J Infect Dev Ctries

View full text Add to dashboard Cite

We report a case of Enterococcus gallinarum meningitis in a 53-year-old female who was admitted to our hospital with a fever, headache, and consciousness disturbance one week after a life-saving craniotomy operation. There was obvious neck stiffness; lumber puncture was performed and cerebrospinal fluid parameters were consistent with bacterial meningitis. The patient was given ceftriaxone and vancomycin for bacterial meningitis. Cerebrospinal fluid culture yielded an isolate which was identified as Enterococcus gallinarum. The isolate was sensitive to ampicillin, ampicillin/clavulanate, linezolid, moxifloxacin and teicoplanin, but it showed intermediate sensitivity to vancomycin and quinoprism-dalfopristin. Intravenous linezolid, 600 mg every 12 hours, was started. Three days after starting treatment, the patient became afebrile; a repeat lumber puncture two week later showed no white blood cells in cerebrospinal fluid and no bacterial growth. Treatment with linezolid was continued for a total therapy duration of three weeks, after which the patient was discharged in a good condition.

show abstract

Enterococcus gallinarum meningitis in an immunocompetent host: a case report

Cited by 10 publications

References 9 publications

Experience with enterococcal meningitis/ventriculitis in children

Experience with enterococcal meningitis/ventriculitis in children

The first case report of Enterococcus gallinarum meningitis in neonate

Enterococcus gallinarum meningitis: a case report and literature review

Contact Info

Product

Resources

About