Human toxocariasis: humoral response (IgG, IgA and IgE) anti-Toxocara canis and clinical-laboratorial correlation in patients following chemotherapy

Rubinsky-Elephant, Guita

doi:10.1590/s0036-46652004000200015

Cited by 4 publications

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“…Its main aetiological agent is the Toxocara canis nematode, and less frequently Toxocara cati, whose final hosts are the dog and cat, respectively (Rubinsky 2004;Radman et al 2006;Marino et al 2011). It is acquired through the ingestion of embryonated eggs exposed to infected soil, geophagy, poorly washed hands, onychophagy, as well as the ingestion of vegetables with animal faeces and larvae encysted in the tissue of paratenic hosts (various animals) (Del Valle et al 2002;Strube et al 2013;Ferrero et al 2014).…”

Section: Seroprevalence Larva Migrans Zoonoses Elisamentioning

confidence: 99%

Presence of Anti-Toxocara Antibodies in Sheep from the State of Mexico

Núñez¹,

Heredia²,

Aguilar³

et al. 2016

Acta Vet. Brno

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Toxocariasis is a parasitic zoonosis caused by the nematode Toxocara canis, and less frequently Toxocara cati, whose final hosts are the dog and cat, respectively. It is acquired by the ingestion of embryonated parasite eggs; the ingestion of meat from animals carrying cystic larvae plays a central role in this disease. The study was conducted in Ayapango, Mexico. Ninety-two sheep where used, of which 72 were females and 20 males. The total prevalence of anti-Toxocara antibodies was 15.21% (14/92), ranging from 17.24% in the one to six months age group to 14.28% in the group older sheep six months, with a higher percentage in females (19.44%) compared to males (5.0%), with a significant difference between positive males and females older than six months of age (Chi-square test = 4.22, P < 0.05). The prevalence of antiToxocara antibodies in sheep suggests that a high number of animals are infected with Toxocara spp. The consumption of meat from paratenic hosts, including sheep, is considered a means of transmission of toxocariasis to humans. Seroprevalence, larva migrans, zoonoses, ELISAToxocariasis is one of the most commonly reported helminth zoonotic infections throughout the world. Its main aetiological agent is the Toxocara canis nematode, and less frequently Toxocara cati, whose final hosts are the dog and cat, respectively (Rubinsky 2004;Radman et al. 2006;Marino et al. 2011). It is acquired through the ingestion of embryonated eggs exposed to infected soil, geophagy, poorly washed hands, onychophagy, as well as the ingestion of vegetables with animal faeces and larvae encysted in the tissue of paratenic hosts (various animals) (Del Valle et al. 2002;Strube et al. 2013;Ferrero et al. 2014). These animals host hypobiotic larvae in the liver and other tissues, which can be transmitted to humans through the ingestion of raw or undercooked meat (De La Fé et al. 2006;Lescano et al. 2012). However, there is little information available on the prevalence of T. canis infection in humans trough paratenic hosts such as horses, sheep, birds, etc. (Alvarez et al. 2011). The objective of the present study was to determine the presence of Toxocara antibodies in sheep of Ayapango, Mexico State, Mexico. Materials and MethodsThis study was conducted from September to November 2013 in the municipality of Ayapango, Mexico (19°10' N, 98°45' W and 2,450 metres above sea level). Ninety-two sheep were used, within the age range from one to 24 months, of which 72 were females and 20 were males. Jugular venipuncture blood samples were taken to measure the level of anti-Toxocara antibodies. The selection of all of the animals included in this study followed random allocation criteria.The anti-Toxocara IgG antibody levels were evaluated using a commercial kit SCIMEDX Toxocara Microwell Serum ELISA indirect format, using antigen excretion/secretion of Toxocara larvae 2, with a dilution of 1:64 test samples, and using protein "A" conjugated to peroxidase. Reading of optical densities was conducted with a spectrophotometer (Vi...

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Section: Seroprevalence Larva Migrans Zoonoses Elisamentioning

confidence: 99%

Presence of Anti-Toxocara Antibodies in Sheep from the State of Mexico

Núñez¹,

Heredia²,

Aguilar³

et al. 2016

Acta Vet. Brno

View full text Add to dashboard Cite

show abstract

“…A sorologia apresenta algumas limitações como reações cruzadas com antígenos de outros helmintos frequentes no homem. O método de Western blotting é usado como confirmatório do teste positivo do ELISA-TES, porém, com algumas limitações como a não distinção entre infecção recente e antiga, e reinfecções ou reativação de larvas em quiescência (13)(14)5) . Por meio do hemograma, é possível detectar o número de eosinófilos que estão aumentados na infecção por Toxocara spp.…”

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