2003
DOI: 10.1590/s0036-46652003000300007
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Chronic interstitial pneumonitis in dogs naturally infected with Leishmania (Leishmania) chagasi: a histopathological and morphometric study

Abstract: SUMMARYEighteen mongrel dogs of unknown age and naturally infected with Leishmania (Leishmania) chagasi, were obtained from the City Hall of Belo Horizonte, Brazil. Four dogs were used as control. Lung samples were obtained and immediately fixed in formalin. The histopathological picture of all lung tissue sections was a chronic and diffuse interstitial pneumonitis. The thickened interalveolar septa were characterized by the cellular exudate (mostly macrophages, lymphocytes and plasmocytes) associated with col… Show more

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Cited by 30 publications
(52 citation statements)
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“…Respiratory alterations include dyspnea, rhinitis, mucocatarrhal nasal discharge, epistaxis, stertorous breath sounds, and chronic interstitial pneumonitis (16,(19)(20)(21). Secondary bacterial or fungal inflammatory processes can be observed in immunosuppressive states, and pneumonia acquires a suppurative aspect (22).…”
Section: Introductionmentioning
confidence: 99%
“…Respiratory alterations include dyspnea, rhinitis, mucocatarrhal nasal discharge, epistaxis, stertorous breath sounds, and chronic interstitial pneumonitis (16,(19)(20)(21). Secondary bacterial or fungal inflammatory processes can be observed in immunosuppressive states, and pneumonia acquires a suppurative aspect (22).…”
Section: Introductionmentioning
confidence: 99%
“…There are contradictions regarding the term pneumonitis. Some authors use it as a synonym for pneumonia while others prefer terms such as pneumonia uremic syndrome (FAUBEL, 2008) or interstitial pneumonitis (DROST, 1997;GONÇALVES, et al, 2003). The term pneumonitis was used in this work to qualify on radiographic images increased diffuse radiopacity of the pulmonary interstitium, classified as interstitial pattern, associated with thickening bronchioles and vasculitis.…”
Section: Resultsmentioning
confidence: 99%
“…is characterised by chronic diffuse interstitial pneumonitis with thickening of the alveolar septa due to the depositing of collagen and a cellular exudates formed principally by macrophages, lymphocytes and plasmatic cells [84]. A similar pulmonary pathology involving foci of septal fibrosis and interstitial pneumonitis with a predominance of mononuclear cells has also been described in humans [85].…”
Section: Genus Leishmaniamentioning
confidence: 86%