Histologic study of colonic mucosa in patients with chronic diarrhea and normal colonoscopic findings

Silva, José Guilherme Nogueira da

doi:10.1590/s0036-46652003000200015

Cited by 19 publications

(25 citation statements)

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“…Because from the histological study of these cases that the diagnosis of diseases as the Crohn's disease (6,26) , intestinal tuberculosis (13) , cytomegalovirus infection (20) and microsporidiasis (26) were possible. On the other hand, YUSOFF et al (24) and SILVA et al (21) verified that the microscopical evaluation of patients with chronic diarrhea and normal ileoscopy did not contribute to their patients diagnosis. The non-utilization of a detailed endoscopic description or classification by these authors did not make possible the comparison with the results obtained in the present study.…”

Section: Discussionmentioning

confidence: 98%

“…Analysing the terminal ileum of 138 patients undergoing colonoscopy, ZWAS et al (26) classified the diagnosis of 4 individuals with diarrhea and normal ileoscopy (Crohn's disease in 2 cases, microsporidiasis in 1 and Mycobacterium avium growth in 1). YUSOFF et al (24) and SILVA et al (21) , respectively studying 152 and 162 patients with chronic diarrhea and normal ileoscopy, established that the terminal ileum biopsies were not useful in the diagnosis of these cases.…”

Section: Introductionmentioning

confidence: 99%

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Terminal ileum of patients who underwent colonoscopy: endoscopic, histologic and clinical aspects

Melo

Cury

Ronchi

et al. 2009

Arq. Gastroenterol.

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-Context -For the diagnosis of the diseases which affect the terminal ileum, the colonoscopy allows macroscopic evaluation and the performing of biopsies. Studies with criteria for the endoscopic and histological characterization of this segment are scarce and there are still some doubts about the need of biopsies in patients with normal ileoscopy. Objective -Study the terminal ileum of patients who underwent colonoscopy considering: endoscopic and histological correlation; agreement between results of the initial histological evaluation and slides review, and the chance of subjects with normal ileoscopy with abdominal pain and/or chronic diarrhea to show histological alterations.Methods -In a prospective study, 111 patients who presented smooth mucosa without enanthema in the endoscopic exam of the terminal ileum were selected. Biopsies of the ileal mucosa of such patients were performed, being the slides routinely examined and reviewed afterwards. Results -The correlation between patients with normal ileoscopy and ileum with preserved histological architecture was of 99.1%. The agreement between initial histological evaluation and slides review calculated by the Kappa test was 0.21. In patients with abdominal pain and/or chronic diarrhea, the chance of showing histological alterations was 2.5 times higher than the others. Conclusions -The correlation between endoscopic and histological findings was high. The agreement between the initial histologic evaluation and slides review was not satisfactory. The chance of subjects with normal ileoscopy with abdominal pain and/or chronic diarrhea, showing histological alterations was higher in relation to the asymptomatic ones or with other symptoms, although the clinical importance of this datum was not evaluated.

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Section: Discussionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

Terminal ileum of patients who underwent colonoscopy: endoscopic, histologic and clinical aspects

Melo

Cury

Ronchi

et al. 2009

Arq. Gastroenterol.

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show abstract

“…Similarly, in this study also, tubular adenomas accounted for 75% of neoplastic polyps. [12][13][14][15] In the same study, it was observed that non-specific colitis was seen in 25% of the cases.…”

Section: Discussionmentioning

confidence: 99%

Histopathological spectrum of gastrointestinal lesions - an experience in a tertiary care centre in South India

Prasaad

Rao

2016

Int J Res Med Sci

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“…Several studies have analyzed the microscopic findings of grossly intact-looking colonic mucosa in patients with [38][39][40][41][42]. The prevalence rates of microscopic colitis in these groups have been reported as 9.5-22.0%.…”

Section: Discussionmentioning

confidence: 99%

A Survey about Irritable Bowel Syndrome in South Korea

et al. 2007

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The aims of the present study were: (1) to assess the prevalence of symptom-based irritable bowel syndrome (IBS) in Korean adults, (2) to assess several organic abnormalities which can be found in IBS patients, and (3) to analyze the risk or associated factors that influence the presence of IBS. Adult health examinees were requested to fill out a questionnaire. The prevalence of IBS was calculated using Rome II criteria. Using several tests, several organic abnormalities were identified in the IBS group. Risk factors were analyzed by comparing the IBS and normal groups. The prevalence value for IBS according to Rome II criteria was 16.8%. Mucosal hyperplasia, lymphocyte aggregation, and increased eosinophil counts were relatively common microscopic findings in IBS group. Female gender, self-consciousness of IBS, and irregular defecation were expressed as significantly independent risk or associated factors for IBS. Several colonic microscopic findings mentioned above may be helpful in accurate diagnosis of IBS. Therefore a more-precise and large population study about these findings is necessary to reach a definitive conclusion.

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Histologic study of colonic mucosa in patients with chronic diarrhea and normal colonoscopic findings

Abstract: SUMMARY OF THESIS*SILVA, José Guilherme Nogueira da -Estudo histológico da mucosa colônica em pacientes com diarréia crônica e colonoscopia normal. São Paulo, 2003.

Cited by 19 publications

References 0 publications

Terminal ileum of patients who underwent colonoscopy: endoscopic, histologic and clinical aspects

Terminal ileum of patients who underwent colonoscopy: endoscopic, histologic and clinical aspects

Histopathological spectrum of gastrointestinal lesions - an experience in a tertiary care centre in South India

A Survey about Irritable Bowel Syndrome in South Korea

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