Blood-sucking lice may disseminate Trypanosoma cruzi infection in baboons

Argañaraz, Enrique R.; Hubbard, Gene B.; Ramos, Larissa Acosta; Ford, Allen L.; Nitz, Nadjar; Leland, M. Michelle; VandeBerg, John L.; Teixeira, Antônio R. L.

doi:10.1590/s0036-46652001000500007

Cited by 26 publications

(15 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Mortality due to locally acquired T. cruzi infection has occurred in groups of captive animals in the United States, including baboons (Papio hamadryas), rhesus macaques, crab-eating macaques (M. fascicularis), Celebes black macaques (M. nigra), sugar gliders (Petaurus breviceps), and a hedgehog (Atelerix albiventris) (8,115,145,213,313). Asymptomatic T. cruzi infection has been reported in lion-tailed macaques (M. silenus), pigtailed macaques (M. nemestrina), rhesus macaques, baboons, ring-tailed lemurs (Lemur catta), and black and white ruffed lemurs (Varecia variegata) in the United States (11,128,145,232,264).…”

Section: Domestic and Exotic Animal Infections In The United Statesmentioning

confidence: 99%

Trypanosoma cruzi and Chagas' Disease in the United States

et al. 2011

View full text Add to dashboard Cite

SUMMARY Chagas' disease is caused by the protozoan parasite Trypanosoma cruzi and causes potentially life-threatening disease of the heart and gastrointestinal tract. The southern half of the United States contains enzootic cycles of T. cruzi , involving 11 recognized triatomine vector species. The greatest vector diversity and density occur in the western United States, where woodrats are the most common reservoir; other rodents, raccoons, skunks, and coyotes are also infected with T. cruzi. In the eastern United States, the prevalence of T. cruzi is highest in raccoons, opossums, armadillos, and skunks. A total of 7 autochthonous vector-borne human infections have been reported in Texas, California, Tennessee, and Louisiana; many others are thought to go unrecognized. Nevertheless, most T. cruzi -infected individuals in the United States are immigrants from areas of endemicity in Latin America. Seven transfusion-associated and 6 organ donor-derived T. cruzi infections have been documented in the United States and Canada. As improved control of vector- and blood-borne T. cruzi transmission decreases the burden in countries where the disease is historically endemic and imported Chagas' disease is increasingly recognized outside Latin America, the United States can play an important role in addressing the altered epidemiology of Chagas' disease in the 21st century.

show abstract

Section: Domestic and Exotic Animal Infections In The United Statesmentioning

confidence: 99%

Trypanosoma cruzi and Chagas' Disease in the United States

et al. 2011

View full text Add to dashboard Cite

show abstract

“…In 1984, it was discovered that some primates at the SNPRC were infected with T. cruzi 11 ; the animals are possibly bitten by the insect vector while resting or sleeping, but the primary route of infection is believed to be opportunistic eating of the insect vectors. 20 At the SNPRC, complete necropsies are carried out on all animals that die. Over 1,000 necropsies are carried out every year.…”

Section: -15mentioning

confidence: 99%

Correlation between Presence of Trypanosoma cruzi DNA in Heart Tissue of Baboons and Cynomolgus Monkeys, and Lymphocytic Myocarditis

Mubiru¹,

Yang²,

Dick³

et al. 2014

The American Journal of Tropical Medicine and Hygiene

Self Cite

View full text Add to dashboard Cite

Abstract. Trypanosoma cruzi, the causative agent of Chagas' disease, preferentially infects cardiac and digestive tissues. Baboons living in Texas (Papio hamadryas) and cynomolgus monkeys (Macaca fascicularis) have been reported to be infected naturally with T. cruzi. In this study, we retrospectively reviewed cases of animals that were diagnosed with lymphocytic myocarditis and used a polymerase chain reaction (PCR)-based method (S36/S35 primer set) to amplify T. cruzi DNA from archived frozen and formalin-fixed paraffin-embedded (FFPE) cardiac tissues. We show that the PCR method is applicable in archived frozen and FFPE tissues and the sensitivity is in the femtogram range. A positive correlation between PCR positivity and lymphocytic myocarditis in both baboons and cynomolgus monkeys is shown. We also show epicarditis as a common finding in animals infected with T. cruzi.

show abstract

“…If the lice had recently taken a blood meal from an animal that was parasitemic with T. cruzi, it could transmit the disease via oral ingestion of the lice. Such mechanism has been proposed to explain an epidemic of Chagas disease in a research baboon colony (Arganaraz et al 2001). Such grooming behavior has been observed in some Native American groups, though not in those from South America.…”

Section: Bilateral Auditory Exostosesmentioning

confidence: 99%

The Bioarchaeological Value of Human Mummies Without Provenience

Arriaza

Cartmell

Moragas³

et al. 2008

Chungará (Arica)

View full text Add to dashboard Cite

Thirteen spontaneously (naturally) mummified human bodies with little or no available provenience data were examined by inspection, dissection and tissue chemical analysis. The purpose of the study was to test the hypothesis that useful anthropological/ archaeological and biomedical information could be derived from bodies even when no reliable provenience for recovered mummies is known. Results of studies on these 13 bodies enabled recognition of their cultural identity, and indicated probable extensive exposure to cold marine water (diving?) in the form of external auditory exostoses. Analysis also revealed coca leaf-chewing (or ingesting) practices that probably caused premature antemortem tooth loss. Biological studies identified the presence of Chagas disease (American trypanosomiasis) in six of the bodies, two of which probably died of this infection during the acute stage. Tuberculous osteomyelitis was established in two mummies with one revealing multiple septicemic lesions of the miliar type. Healed pneumonia and osteopenia were present in several others, one with multiple compressed vertebral fractures. We conclude that even mummies without provenience data harbor much recoverable information that can be integrated into anthropological and biomedical databases.Key words: Mummies without cultural context, bioarchaeology, Chagas disease, pneumonia, tuberculosis. En este estudio se presentan los análisis morfológicos, osteopatológicos y químicos de trece cuerpos con momificación natural cuyo contexto cultural era pobre o no existente. El propósito de este estudio fue verificar la hipótesis de que a pesar de que los cuerpos no presentaban un contexto arqueológico bien definido, estos podían ser muy útiles para investigar importantes problemas bioarqueológicos y biomédicos de la prehistoria local. Los resultados permitieron ubicar a estos trece cuerpos en un marco cultural y establecer la presencia de exostosis auditivas

show abstract

Blood-sucking lice may disseminate Trypanosoma cruzi infection in baboons

Cited by 26 publications

References 18 publications

Trypanosoma cruzi and Chagas' Disease in the United States

Trypanosoma cruzi and Chagas' Disease in the United States

Correlation between Presence of Trypanosoma cruzi DNA in Heart Tissue of Baboons and Cynomolgus Monkeys, and Lymphocytic Myocarditis

The Bioarchaeological Value of Human Mummies Without Provenience

Contact Info

Product

Resources

About