Dermatophytosis: association between ABO blood groups and reactivity to the trichophytin

Abstract

The authors investigated the relationship between dermatophytosis and ABO blood groups through blood typing, identification of isolated dermatophytes and specific cellular immune response of 40 individuals carriers of this mycosis. They verified that the fungus Trichophyton rubrum, isolated from 54.5% of the patients, was more frequent in individuals belonging to blood group A. The cellular immune response, evaluated through the trichophytin antigen, was positive in 25% of the studied patients; the presence of immediate reactions (30 minutes) was verified in 35%. The blood group distribution among patients with dermatophytosis and control groups was, respectively: 47.5% X 36% in group A, 40% X 50% in group O, 12. 5% X 11% in group B. Even though the authors have found a higher number of patients belonging to blood group A infected by T. rubrum, these results suggest that there is no statistical evidence that these individuals are more susceptible to dermatophytosis.

The Potential Association of Human ABO Blood Group in Candida albicans Germination

“…on the skin mucous membranes and bloodstream, the infections rate was found to be higher in individual with blood group type O compared to other blood group [7,8]. In mold infection, a previous study reported a higher prevalence of dermatophytes infection, among patients with blood group A [9,10]. The study was consistent with Candida spp.…”

HLA in Brazilian Ashkenazic Jews with chronic dermatophytosis caused by Trichophyton rubrum

“…According to the latest studies carried out in Brazil, the most isolated species in chronic infections of tinea ungueum and pedis has been the T. rubrum (6,9,16,23). Although this disease is not serious in terms of mortality or physical sequelae, it has significant clinical consequences, mainly regarding aesthetic and chronic aspects of the infection, besides therapeutics difficulties (17).…”

Freqüências relativas dos fenótipos eritrocitários ABO e Lewis na doença de Jorge Lobo

“…8 De acordo com os autores, os indivíduos que têm esses antígenos eritrocíticos seriam mais suscetíveis ao desenvolvimento de dermatofitoses generalizadas e resistentes ao tratamento do que os indivíduos não providos desses antígenos. Recentemente, Vilani-Moreno et al, 9 ao investigarem a relação entre dermatófitos e grupo sangüíneo ABO, encontraram um número maior de pacientes pertencentes ao grupo sangüíneo A e infectados pelo T. rubrum; entretanto, não obtiveram evidência estatística de que esses indivíduos eram mais suscetíveis às dermatofitoses.…”