DERMATOMYCOSIS OF THE TOE WEB CAUSED BY Curvularia lunata

Phaeohyphomycosis: a clinical-epidemiological and diagnostic study of eighteen cases in Rio Grande do Sul, Brazil

“…Reviewing the relevant literature in RS, we found cases of phaeohyphomycosis (including cases 1, 2, 10 and 15 of the current series, which have been previously published) as follows: peritoneal, one case caused by Curvularia lunata (Lopes et al 1994), cutaneous, one case caused by C. lunata (Lopes & Jobim 1998), subcutaneous, 10 cases, including two cases with only his- topathological diagnoses available (Severo et al 1987), one case caused by E. jeanselmei, one case caused by Phaeoacremonium aleophilum and one caused by Phaeoacremonium rubrigenum (Guarro et al 2003), and systemic, one case caused by Cladophialophora bantiana (Walz et al 1997). Re-evaluation of morphological characteristics, supported by phylogenetic analysis, identified P. aleophilum as a new fungal species, Phaeoacremonium alvesti (Mostert et al 2005).…”

Tiny keratotic brown lesions on the interdigital web between the toes of a healthy man caused by Curvularia species infection and a review of cutaneous Curvularia infections

“…Mahgoub (1973) described the first report of cutaneous Curvularia infection, caused by C. lunata. Thereafter, 25 reports of human skin infection cases in the English and Japanese literature were published (Mahgoub 1973;Rohwedder et al 1979;Barde and Singh 1983;Kiryu and Suenaga 1985;Duvic et al 1987;Gugnani et al 1990;Kamalam et al 1992;Grieshop et al 1993;Harris and Downham 1978;Lavoie et al 1993;Still et al 1993;Yvonne et al 1994;Agrawal and Singh 1995;Berg et al 1995;Torda and Jones 1997;Lopes and Jobim 1998;Fernandez et al 1999;Bonduel et al 2001;Tessari et al 2003;Tamaki et al 2006;Fan et al 2008;Garg et al 2008;Hiromoto et al 2008), including our patient (Table 2). Five species in the genus Curvularia were isolated from the skin lesions.…”

“…In the superficial infected type, 7 cases were reported: pigmented macules (Gugnani et al 1990;Agrawal and Singh 1995), scaling lesion (Lopes and Jobim 1998), and brown thick scales (present case) on the web between the toes and onychomycosis (Barde and Singh 1983;Kamalam et al 1992). Similar to our case, a 50-year-old Caucasian woman with a scaling lesion on the interdigital web between the toes caused by C. lunata was reported from Brazil (Lopes and Jobim 1998). In 24 cases of Curvularia infection, all patients had skin lesions involving the upper or lower extremities, except for 1 case of fungal sternal wound infection in a neonate with congenital heart disease.…”

“…In the deep mycosis type, 16 cases were reported: abscess (mycetomas) (Mahgoub 1973), ulcer (Rohwedder et al 1979;Berg et al 1995, Torda andJones 1997;Hiromoto et al 2008), ecthyma gangrenosum-like lesion (Bonduel et al 2001), firm tender nodules and nodes (Tessari et al 2003;Garg et al 2008), papules (Kiryu and Suenaga 1985;Duvic et al 1987), macular lesion with central necrosis (Fernandez et al 1999), hemorrhagic bullous lesion (Lavoie et al 1993), and others [burn wound (Grieshop et al 1993;Still et al 1993), elevated hyperpigmented scaly lesion (Harris and Downham 1978), and surgical wound (Yvonne et al 1994)]. In the superficial infected type, 7 cases were reported: pigmented macules (Gugnani et al 1990;Agrawal and Singh 1995), scaling lesion (Lopes and Jobim 1998), and brown thick scales (present case) on the web between the toes and onychomycosis (Barde and Singh 1983;Kamalam et al 1992). Similar to our case, a 50-year-old Caucasian woman with a scaling lesion on the interdigital web between the toes caused by C. lunata was reported from Brazil (Lopes and Jobim 1998).…”

“…The patient with a sternal wound infection caused by C. lunata was a neonate with congenital heart disease, who developed multiorgan failure and died (Yvonne et al 1994). Topical application of imidasol was successful for treatment of superficial skin infection by Curvularia (Gugnani et al 1990;Kamalam et al 1992;Lopes and Jobim 1998).…”