Schistosoma mansoni: aspectos quantitativos da fertilidade e sobrevida de vermes oriundos de cercárias irradiadas com 3 Krad, em camundongos

Cardoso, Gileno de Sá; Coelho, Paulo Marcos Zech

doi:10.1590/s0036-46651990000100005

Cited by 2 publications

(2 citation statements)

References 4 publications

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“…12 The LE strain has been maintained for more than 30 years at the Schistosomiasis Research Unit (Laboratory of Dr. José Pellegrino, Federal University of Minas Gerais, Brazil) by serial passage through Biomphalaria glabrata and hamsters (Mesocricetus auratus). Another group of mice were infected with 250 LE cercariae irradiated with 3 Kr of gamma irradiation of Cobalt-60, to sterilize the female worms [13][14][15][16][17] and to prevent the deposition of eggs in the liver parenchyma.…”

Section: Methodsmentioning

confidence: 99%

Pathogenic aspects of pyogenic liver abscess associated with experimental schistosomiasis.

Teixeira

Coelho²,

Filho³

et al. 2001

The American Journal of Tropical Medicine and Hygiene

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Abstract. Schistosomiasis mansoni infection that occurs concurrently with Staphylococcus aureus bacteremia favors the formation of pyogenic liver abscess. The present experimental study in mice evaluated the following aspects of the relationship between infection with Schistosoma mansoni and liver abscess caused by S. aureus: a) the role of the eggs of S. mansoni in the genesis of the abscesses; b) the influence of different phases of schistosomiasis in the development of liver abscesses; and c) the effect of the treatment of schistosomiasis on the development of the abscesses. Macroscopic and histopathological study showed multiple liver abscesses around granulomas of S. mansoni in the acute and chronic phases of schistosomiasis. Treatment of acute schistosomiasis before experimentally-induced bacteremia did not prevent the formation of liver abscess. The study findings indicate that granulomas around S. mansoni eggs and worms lodged in the liver provide a focus and substrate for pyogenic abscesses caused by S. aureus.

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Section: Methodsmentioning

confidence: 99%

Pathogenic aspects of pyogenic liver abscess associated with experimental schistosomiasis.

Teixeira

Coelho²,

Filho³

et al. 2001

The American Journal of Tropical Medicine and Hygiene

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“…Our study revealed that rotifer exposure can significantly affect the development of B. straminea snails according to the shell diameter results, implying a potential influence on the reproduction and maturity of Biomphalaria snails. Previous studies revealed that there was an increase in growth inhibition in S. mansoni-infected snails (Looker and Etges, 1979;Meier and Meier-Brook, 1981;Cardoso and Coelho, 1990). Therefore, the growth of rotiferexposed snails was similar to that of S. mansoni-infected snails.…”

Section: Discussionmentioning

confidence: 76%

Molecular Characterization of Rotifers and Their Potential Use in the Biological Control of Biomphalaria

Lin

Xiang

Sanogo

et al. 2021

Front. Cell. Infect. Microbiol.

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BackgroundSchistosomiasis is one of the most important tropical parasitic diseases worldwide. Biomphalaria straminea, the intermediate host of Schistosoma mansoni, has invaded and spread to Southern China since 1974 and may pose enormous threats to public health. Controlling intermediate host snails is an effective strategy in schistosomiasis intervention. However, the only effective chemical molluscicide, niclosamide, currently recommended by WHO may cause environmental pollution, loss of biodiversity, and high costs. Thus, to counter intermediate hosts, a sustainable and environmentally friendly tool is urgently needed. Here, we conducted field investigations to collect and identify a potential snail competitor rotifer and evaluated its molluscicide effect.ResultsIn this study, we collected two samples of rotifers from Shenzhen. We found both red and black phenotypic B. straminea snails at the sampling sites. We identified the rotifer population as a species of the genus Philodina according to the amplification and phylogenetic analysis results of coxI gene. We found that rotifer exposure did not significantly affect the hatching rate of B. straminea eggs but promoted the killing of juvenile snails. Meanwhile, rotifer exposure did not significantly alter the fecundity of B. straminea quantified by the number of eggs per egg mass, the number of egg masses per snail, and the number of eggs per snail; but the snails exposed to rotifers showed lower fecundity performance than the control snails. Importantly, rotifer exposure could significantly affect the development of juvenile B. straminea, showing a smaller shell diameter of the exposed snails than that of the control snails. In addition, rotifer exposure affected the life span of B. straminea snails, showing a 16.61% decline in the average life span. After rotifer exposure, the S. mansoni-infected B. straminea snails died significantly faster than those without rotifer exposure. Similar findings were observed in S. mansoni-infected Biomphalaria glabrata snails. These results implied that rotifer exposure significantly promoted the mortality of S. mansoni-infected B. straminea and B. glabrata.ConclusionsOur study demonstrated the potential molluscicide effect of rotifers on intermediate hosts under laboratory conditions. Our findings may provide new insights into the development of biocontrol strategies for snail-borne disease transmission.

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Schistosoma mansoni: aspectos quantitativos da fertilidade e sobrevida de vermes oriundos de cercárias irradiadas com 3 Krad, em camundongos

Cited by 2 publications

References 4 publications

Pathogenic aspects of pyogenic liver abscess associated with experimental schistosomiasis.

Pathogenic aspects of pyogenic liver abscess associated with experimental schistosomiasis.

Molecular Characterization of Rotifers and Their Potential Use in the Biological Control of Biomphalaria

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