1989
DOI: 10.1590/s0036-46651989000500004
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Schistosoma mansoni: aspectos quantitativos da evolução de cercarias irradiadas a nível da pele, pulmões e sistema porta, em camundongos

Abstract: RESUMOFoi estudada a migração do Schistosoma mansoni (cepas LE e SJ) em oito grupos de camundongos albinos (Mus musculus) não isogênicos, infectados transcu¬ taneamente com cerca de 450 cercárias não irradiadas (grupos controles) e irradiadas com 3 Krad, 20 Krad e 40 Krad de radiação gama proveniente de cobalto-60. Na pele, observou-se uma diminuição progressiva das taxas de recuperação em função do tempo e, nos pulmões e sistema porta, verificou-se uma relação inversa significativa entre as taxas de recuperaç… Show more

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(1 citation statement)
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“…12 The LE strain has been maintained for more than 30 years at the Schistosomiasis Research Unit (Laboratory of Dr. José Pellegrino, Federal University of Minas Gerais, Brazil) by serial passage through Biomphalaria glabrata and hamsters (Mesocricetus auratus). Another group of mice were infected with 250 LE cercariae irradiated with 3 Kr of gamma irradiation of Cobalt-60, to sterilize the female worms [13][14][15][16][17] and to prevent the deposition of eggs in the liver parenchyma.…”
Section: Methodsmentioning
confidence: 99%
“…12 The LE strain has been maintained for more than 30 years at the Schistosomiasis Research Unit (Laboratory of Dr. José Pellegrino, Federal University of Minas Gerais, Brazil) by serial passage through Biomphalaria glabrata and hamsters (Mesocricetus auratus). Another group of mice were infected with 250 LE cercariae irradiated with 3 Kr of gamma irradiation of Cobalt-60, to sterilize the female worms [13][14][15][16][17] and to prevent the deposition of eggs in the liver parenchyma.…”
Section: Methodsmentioning
confidence: 99%