“…The effectiveness of Brazilian National Health Innovation System (SNIS) is limited, among other factors, by low communication rate between the organizations and institutions in the SNIS, contrary to the trend in more mature innovation systems 29 . In addition, structural problems in Brazilian society such as extreme inequality, poor quality of education, precarious infrastructure, precarious information technology in the national territory, and an adverse tax system vis-à-vis productivity also affect and limit the capacity to produce and innovate Brazilian health industries 20,30 . In technological terms, the country has witnessed the growing leadership of biotechnology in the health area, which involves, for example, the use of genetic engineering for the production of biopharmaceuticals, vaccines, and gene therapy, besides the application of pharmacogenetics tools, aimed at the development of more personalized therapies 8 .…”