Hepatites B e C em usuários de drogas injetáveis vivendo com HIV em São Paulo, Brasil

Abstract

OBJECTIVE:To describe the profi le of injecting drug users living with HIV/AIDS and estimate hepatitis B and hepatitis C prevalence rates within this group. METHODS:Cross-sectional study conducted with 205 injecting drug users living with HIV/AIDS receiving attention in three public health clinics in the city of Sao Paulo, in 2003. A non-probabilistic sample of volunteers was selected consecutively on the days respondents appeared for their appointments at the clinics. Personal data and information on sexual behavior, drug use and knowledge of hepatitis was collected through interviews. Tests were conducted to detect infections of the hepatitis B and C viruses. RESULTS:Out of the interviewees, 81% were men and 19% women, with an average age of 39 (SD = 6.1) and six years of formal education (SD = 2.0). There was no difference in marital status between the sexes, of which 48% were single, 42% were married, and 8% were divorced. The average ages for fi rst use of tobacco, alcohol and illegal drugs were 13, 15 and 18, respectively. Hepatitis B and C prevalence were 55% (95% CI: 49;63) and 83%(95% CI: 78;88), respectively. Eighty percent of respondents had not heard of Hepatitis B and C prior to the fi rst time they used injecting drugs. CONCLUSIONS:The high prevalence rates of Hepatitis B and C and low level of knowledge regarding the diseases justify the inclusion of information about hepatitis infections and the hepatitis B vaccines in HIV harm reduction strategies.

Prevalence, risk factors and genotypes of hepatitis B infection among HIV-infected patients in the State of MS, Central Brazil

“…The prevalence of HBV infection among HIV-infected patients measured in this study (26.2%) was lower than those reported in sub-Saharan Africa (59.8%), 16 Chile (46.3%), 17 Cuba (45.5%) 18 and in different regions of Brazil, which ranges from 30.0% to 55.1%. 4,5,7,19,20 The prevalence of HIV-HBV coinfection (2.5%) in the present study was lower than those reported in different regions of Brazil (5.7%, 8.5%, and 18%). 4,5,21 In addition, our results were in line with the prevalence of HIV-HBV coinfection from the state of Mato Grosso, also located in Central-West Region of Brazil.…”

“…Most of the studies, conducted in South and Southeast regions of Brazil, have reported HIV-HBV coinfection prevalence, ranging from 2.3% to 27.3%. [3][4][5][6][7] Furthermore, this is the first study reporting the HBV genotypes in HIV infected individuals in Central-West Region of Brazil.…”

Hepatitis B, C and Hiv Co-Infections Seroprevalence in a Northeast Brazilian Center

“…In Brazilian North-Northeast regions, 0.2% to 0.6% of the individuals with ages ranging from 13 to 69 years is HBsAg positive (10) . This prevalence is particularly elevated in high risk populations, such as drug addicted individuals (27,3%) (8) . An overall HCV prevalence of 2.5% to 10% has been estimated by the WHO in Brazil (18) .…”

Substance Abuse, HIV-1 and Hepatitis

“…A number of studies and reviews have reported and discussed the prevalence of HIV-1 and hepatitis coinfection in a substance-abusing population [157-160]; however, few of these studies considered the molecular effects of substance abuse on the two infections [161, 162]. A recent study evaluated liver fibrosis among 497 patients, including HCV-monoinfected and HIV/HCV-coinfected substance abusers for whom opiates and cocaine were the dominant drugs of choice.…”