Alteração de enzimas hepáticas em trabalhadores de refinaria de petróleo

Carvalho, Fernando Martins; Neto, Annibal Muniz Silvany; Mendes, João Luiz Barberino; Cotrim, Helma Pinchemel; Nascimento, Ana Lísia Cunha; Júnior, Alberto Soares Lima; Cunha, Tatiana Oliveira Bernardo da

doi:10.1590/s0034-89102006000100015

Cited by 10 publications

(2 citation statements)

References 13 publications

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“…In 2006, petrochemical workers revealed considerable increase in their liver transaminases compared with non-exposed individuals [19]. Liver enzymes disorders were also identified among 150 refinery workers in a case-control study by Carvalho [20]. In a study by Dossing, et al, 3 chemical plant workers became jaundiced and showed hepatic necrosis due to occupational exposure to carbon disulphide, isopropanol, toluene, and acrylonitrile for 2 to 4 months [21].…”

Section: Discussionmentioning

confidence: 99%

A Survey on Chemical Hazards and Liver Function in Rubber Industry Workers in Iran

Rafeemanesh¹,

Bazzaz²,

Sadrossadat

et al. 2015

IJCM

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Rubber industries workers are at risk of hepatic dysfunction from exposure to rubber dust and a mixture of different hydrocarbons. This study aimed to evaluate the relation between chemical hazards in workplace and serum hepatic transaminases in rubber industry workers in Iran. This historical cohort study was conducted in a rubber-manufacturing industry in Mashhad. It consisted of 91 workers with chemical substances exposure and 85 workers not exposed to chemicals. Hepatic transaminases including alanine transaminase (ALT) and aspartate transaminase (AST) were compared between these two groups. Required data were collected through questionnaire, liver enzymes evaluation, and environmental monitoring of chemical substances. The data were analyzed with SPSS 11.5. A total of 176 workers enrolled in this study included 113 (64.2%) male and 73 (35.8%) female. The mean of age and employment duration in exposed group were 29.22 ± 3.99 and 5.41 ± 2.77 and in non-exposed group were 30.33 ± 4.11 and 5.29 ± 2.77 respectively. The mean of ALT in exposed and non-exposed groups was 31.3 ± 8.04 and 23.8 ± 10.42 (p = 0.01) and the mean of AST was 29.6 ± 9.7 and 27.3 ± 8.2 (p = 0.1) respectively. A significant difference was shown between mean of ALT at the date of employment and at the time of the study in exposed group. According to our findings evaluation of serum transaminases is a useful screening method which might be beneficial in early detection of hepatocellular injuries in rubber industry workers.

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Section: Discussionmentioning

confidence: 99%

A Survey on Chemical Hazards and Liver Function in Rubber Industry Workers in Iran

Rafeemanesh¹,

Bazzaz²,

Sadrossadat

et al. 2015

IJCM

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“…The traditional biomarkers of chronic alcohol consumption, used frequently in the clinic (mean corpuscular volume [MCV], ALT, AST and GGT) are modified in the same manner both in the chronic alcoholic hepatitis and in occupational hepatitis caused by exposure to hydrocarbons. Occupational exposure in a refinery remained significantly associated with a significant increase in the elevation of GGT and ALT even after correcting for obesity and alcohol consumption [7]. GGT is also increased in cholestasis and cholestatic adverse effects of aromatic hydrocarbons (elevation of GGT and alkaline phosphatase) have been described as well [8].…”

Section: Commentsmentioning

confidence: 99%

Differential diagnosis between occupational chronic intoxication with organic solvents and ethanol abuse by biological markers. Case report and literature review

Rașcu

Naghi

Arghir

et al. 2016

ARS Medica Tomitana

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Given the occupational exposure to substances contained in petroleum heated to high temperature, cholestatic liver disease, neurological signs and symptoms can occur. We present a case report of a male patient with no tobacco exposure or alcohol use, but with prolonged occupational exposure to petroleum vapours and natural gases like methane, propane butane who developed liver and neurologic disease, in the absence of protective equipment. Delayed diagnosis was established after 9 years of the first symptoms occurrence. Differential diagnosis with alcoholic etiology was considered and biological biomarkers were useful.

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Effect of petroleum wastewater treated with gravity separation and magnetite nanoparticles adsorption methods on the blood biochemical response of mrigal fish (Cirrhinus cirrhosus)

Hamidi¹,

Banaee²,

Pourkhabbaz³

et al. 2021

Environ Sci Pollut Res

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Alteração de enzimas hepáticas em trabalhadores de refinaria de petróleo

Abstract: Objective

Cited by 10 publications

References 13 publications

A Survey on Chemical Hazards and Liver Function in Rubber Industry Workers in Iran

A Survey on Chemical Hazards and Liver Function in Rubber Industry Workers in Iran

Differential diagnosis between occupational chronic intoxication with organic solvents and ethanol abuse by biological markers. Case report and literature review

Effect of petroleum wastewater treated with gravity separation and magnetite nanoparticles adsorption methods on the blood biochemical response of mrigal fish (Cirrhinus cirrhosus)

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