Valores de referência para carboxiemoglobina

Siqueira, María Elisa Pereira Bastos de; Martins, Isarita; Costa, Andréia Cristina Barbosa; Andrade, Eronice L.; Esteves, Maria Tereza C.; Lima, Selmo A.

doi:10.1590/s0034-89101997000700010

Cited by 7 publications

(7 citation statements)

References 9 publications

(3 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…To evaluate HIV disease stage we can measure for absolute counts and percentage of T lymphocytes, coupled with HIV RNA viral load measurement [4]. Reference range values are used for clinical monitoring of patients and are defined by normal parameters values from healthy population [5].…”

mentioning

confidence: 99%

Reference range for T lymphocytes populations in blood donors from two different regions in Brazil

Torres¹,

Angelo²,

Netto³

et al. 2009

Braz J Infect Dis

View full text Add to dashboard Cite

This study defined the normal variation range for different subsets of T-lymphocyte cells count in two different Brazilian regions. We analysed the T-lymphocytes subpopulations (CD3+, CD4+, CD8+) in blood donors of two Brazilian cities, located in North (Belem, capital state of Para, indian background) and Northeast (Salvador, capital state od Bahia, African background) regions of Brazil. Results were compared according to gender, stress level (sleep time lower than 8 hours/day), smoking, and alcohol intake. Lymphocytes subpopulations were measured by flow cytometry. Five hundred twenty-six blood donors from two Brazilians cities participated in the study: 450 samples from Bahia and 76 samples from Pará. Most (60%) were men, 59% reported alcohol intake, 12% were smokers, and 80% slept at least 8 h/day. Donors from Bahia presented with significantly higher counts for all parameters, compared with Para. Women had higher lymphocytes levels, in both states, but only CD4+ cells count was significantly higher than men's values. Smokers had higher CD4+ counts, but sleep time had effect on lymphocytes levels only for Para's donors (higher CD3+ and CD4+ counts). That state had also, a higher proportion of donors reporting sleep time <8 h/day. The values for CD3, CD4 and CD8+ cells count were significantly higher in blood donors from Bahia than among those from Pará. Female gender, alcohol intake, stress level, and smoking were associated with higher lymphocyte counts. The use of a single reference range for normal lymphocytes count is not appropriate for a country with such diversity, like Brazil is.

show abstract

mentioning

confidence: 99%

Reference range for T lymphocytes populations in blood donors from two different regions in Brazil

Torres¹,

Angelo²,

Netto³

et al. 2009

Braz J Infect Dis

View full text Add to dashboard Cite

show abstract

“…Dentre as vítimas submetidas à dosagem de COHb, 33,2% encontrava-se abaixo de 9% e em 32,6% dos casos a concentração de COHb encontrada estava na faixa de 10 a 80%. De acordo com Marshall et al (1995) indivíduos não fumantes expostos ao CO apresentam concentrações de COHb, sem relato de danos, entre 0,4 e 6,0% e indivíduos com nicotina e/ou seus metabolitos no sangue variam a concentração de COHb entre 1 e 7% [13][14][15] .…”

Section: Discussionunclassified

“…É importante o relato de lesões existentes no cadáver pelo médico legista durante o exame necroscópico, possibilitando determinar o momento em que o indivíduo entrou em contato com a ação do fogo 4,14 . Neste estudo, há vários casos de mortes por consequência de ação de instrumentos perfuro-cortantes e perfuro-contundentes (2010 e2015), além de outras causas relatadas anteriormente, assim como causas indeterminada da morte (2014), e esse fato pode estar associado com a dificuldade e complexidade de realizar-se um exame necroscópico em vítimas carbonizadas 4,11 .…”

Section: Discussionunclassified

Caracterização do perfil epidemiológico de vítimas carbonizadas necropsiadas no IML-SP entre 2010 e 2015

et al. 2017

View full text Add to dashboard Cite

RESUMO: O monóxido de carbono faz parte do grupo dos poluentes gasosos e pode agir como um poderoso asfixiante químico, sendo responsável por elevadas taxas de mortalidade no mundo. Quando inalada, essa substância se difunde facilmente pela membrana alvéolo-capilar, e, uma vez na corrente sanguínea, liga-se facilmente à hemoglobina, devido à alta afinidade existente entre esta molécula e o monóxido de carbono. Consequentemente, quando o monóxido de carbono é ligado a hemoglobina, ele assume uma nova conformação irreversível, chamada de carboxihemoglobina. No estado de São Paulo, os cadáveres carbonizados são periciados no Instituto Médico-Legal, mais especificamente no núcleo da Antropologia Forense, área especializada na aplicação do conhecimento antropológico que tem como um dos objetivos identificar o indivíduo e diagnosticar a causa da sua morte. O estudo da concentração de monóxido de carbono no cadáver permite inferir se a carbonização ocorreu ante ou post mortem. Esta informação é altamente importante em termos legais para a aplicação de penalidades, em casos criminais. O objetivo do presente estudo foi caracterizar o perfil epidemiológico das vítimas carbonizadas necropsiadas entre os anos de 2010 e 2015, a fim de estabelecer se o óbito ocorreu antes ou após a carbonização. Os dados de 214 vítimas foram estudados e as informações coletadas foram agrupados de acordo com gênero, faixa etária, raça, local onde o corpo foi encontrado, causa da morte, presença ou ausência do Sinal de Montalti e concentração de carboxihemoglobina. Quanto ao perfil das vítimas, a maioria era do sexo masculino (78,5%), tinha raça branca (39,2%) e idade entre 16 e 47 anos (90,4%). A causa da morte variou entre os anos estudados, os corpos foram encontrados com maior frequência nas vias públicas (36,4%), em 48,1 % dos cadáveres o Sinal de Montalti estava ausente e em 33,2% dos casos a carboxihemoglobina estavam abaixo de 9%. Assim, estes dados permitem concluir que a maioria dos indivíduos estavam sem vida quando ocorreram as lesões pelo fogo, ou seja, a carbonização ocorreu post mortem.

show abstract

“…To perform the maneuver, the worker remained seated, performing a maximum inspiration until the total lung capacity (TLC), followed by a 20-second apnea to balance blood CO levels with alveolar CO, slowly exhaling until residual volume (RV). Reference parameters of 6 ppm for COex (SANTOS et al, 2001), and 2.5% for COHb were used (SIQUEIRA et al,1997). Values were obtained before the start of the workday, followed by four more evaluations, respectively, after 60, 120, 180 and 240 minutes of exposure smoke from barbecue grill.…”

Section: Methodsmentioning

confidence: 99%

Levels of exhaled carbon monoxide in steakhouse workers in a town in the Brazilian Legal Amazon region

Oliveira

Pinto

Capeleto

et al. 2022

CeN

View full text Add to dashboard Cite

Occupational exposure to smoke from commercial kitchens such as steakhouses may be associated with an increase in the prevalence of respiratory symptoms and an acute reversible decrease in pulmonary functional capacity, and exposure to coal smoke is a risk factor for the development of respiratory diseases. The objetive of study was evaluate the levels of exhaled carbon monoxide (COex) and carboxyhemoglobin (COHb) in steakhouse workers. This is an observational, longitudinal and prospective study in the city of Cuiabá, Mato Grosso, Brazil. The total of 29 professionals working in steakhouses participated in the study. Data on socio-demographic characteristics, work environment characteristics, life habits and respiratory symptoms were extracted from questionnaires. COex and COHb levels were measured before exposure and every hour up to a 4 hour exposure period. Twenty-nine workers participated, with a predominance of females (55.2%), with a mean age of 36.40±11.49 years. It was observed that 18 (62%) of the workers had respiratory symptoms. COex and COHb levels were elevated after 4 hour exposure (p<0.05), but within acceptable parameters. COex and COHb levels are elevated in a short period of time to occupational exposure to steakhouse activities.

show abstract

Valores de referência para carboxiemoglobina

Cited by 7 publications

References 9 publications

Reference range for T lymphocytes populations in blood donors from two different regions in Brazil

Reference range for T lymphocytes populations in blood donors from two different regions in Brazil

Caracterização do perfil epidemiológico de vítimas carbonizadas necropsiadas no IML-SP entre 2010 e 2015

Levels of exhaled carbon monoxide in steakhouse workers in a town in the Brazilian Legal Amazon region

Contact Info

Product

Resources

About