Interação de fatores riscos em tuberculose

Ruffino-Netto, Antônio; Caron-Ruffino, Márcia

doi:10.1590/s0034-89101979000200008

Cited by 4 publications

(4 citation statements)

References 2 publications

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“…The present study found no association between alcohol consumption and TB, which differs from other studies which concluded that alcohol had a stronger association with tuberculosis [ 11 ]. Ruffino-Neto, several decades ago, investigated the role of alcohol consumption and smoking in the risk of developing tuberculosis and found that smoking was associated with tuberculosis only in the group of drinkers [ 12 , 13 ]. However, alcoholics should also be counseled effectively to wean them away from these unhealthy behaviors and minimize the risk of developing the disease.…”

Section: Discussionmentioning

confidence: 99%

A case control study of risk factors associated with pulmonary tuberculosis in Romania: Experience at a clinical hospital of pneumology

Ndishimye

Domokos

Stillo

et al. 2017

Medicine and Pharmacy Reports

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Background and aimTuberculosis (TB) remains a major public health issue in Romania. The aim of the present study was to evaluate the potential demographic, socioeconomic and behavioral risk factors for TB among hospitalized patients in Romania.MethodsThis is a case-control study conducted between March 1st 2014 and March 30th 2015 at Leon Daniello Clinical Hospital of Pneumology, Cluj Napoca. A total of 150 TB patients defined as “cases” were matched for age, sex and county of residence to 150 controls selected from patients attending the same hospital with respiratory diseases other than TB. Data collection was obtained through patient interviews using a structured questionnaire. Factors potentially associated with TB infection were analyzed using univariate and multivariate logistic regression.ResultsFactors independently associated with TB were illiteracy (OR=2.42, 95% CI 1.09–5.37), unemployment (OR=2.08, 95% CI 1.23–3.53), low household income (OR=4.12, 95% CI 2.53–6.71), smoking (more than 20 cigarettes per day) (OR=2.12, 95% CI 1.20–3.74), poor knowledge of TB (OR=3.46, 95% CI 1.97–6.07), presence of TB patient in household (OR=4.35, 95% CI 1.42–13.36), prior TB treatment (OR=2.2, 95% CI 1.93–2.5) and diabetes (OR=3.32, 95% CI 1.36–8.08).ConclusionThis study provided useful information that might help to develop and adapt effective policies for TB control in Romania.

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Section: Discussionmentioning

confidence: 99%

A case control study of risk factors associated with pulmonary tuberculosis in Romania: Experience at a clinical hospital of pneumology

Ndishimye

Domokos

Stillo

et al. 2017

Medicine and Pharmacy Reports

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“…did not control for smoking, and if alcohol and tobacco consumption are associated in that setting, the association measured may be reflecting an unmeasured effect of smoking. In relation to the role of alcohol consumption and smoking in the risk of developing tuberculosis (rather than relapsing), Ruffino-Neto and Ruffino, 19 several decades ago, investigated the synergism between these two factors and found that smoking was associated with tuberculosis only in the group of drinkers (alcohol), whereas Brown and Campbell, on examining confounding between the two variables, concluded that alcohol had a stronger association with tuberculosis. 20 Due to these findings, smoking was adjusted for alcohol consumption in the present study, but there was no confounding effect between alcohol consumption and smoking on the risk of relapse (data not shown).…”

Section: Discussionmentioning

confidence: 99%

“…Despite the fact that in the second half of the last century several studies pointed to an association between smoking and developing tuberculosis, 19 , 21 , 22 there was a gap of decades until scientific interest in this topic was renewed. More recently, studies have investigated and found evidence of smoking as a risk factor for developing tuberculosis, independently, or interacting with alcohol consumption, and evidence of progression from latent tuberculosis infection to disease.…”

Section: Discussionmentioning

confidence: 99%

Smoking increases the risk of relapse after successful tuberculosis treatment

Batista

Albuquerque

Ximenes

et al. 2008

International Journal of Epidemiology

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Background Recent tobacco smoking has been identified as a risk factor for developing tuberculosis, and two studies which have investigated its association with relapse of tuberculosis after completion of treatment had conflicting results (and did not control for confounding). The objective of this study was to investigate risk factors for tuberculosis relapse, with emphasis on smoking.Methods A cohort of newly diagnosed TB cases was followed up from their discharge after completion of treatment (in 2001–2003) until October 2006 and relapses of tuberculosis ascertained during that period. A case of relapse was defined as a patient who started a second treatment during the follow up.Results Smoking (OR 2.53, 95% CI 1.23–5.21) and living in an area where the family health program was not implemented (OR 3.61, 95% CI 1.46–8.93) were found to be independently associated with relapse of tuberculosis.Conclusions Our results establish that smoking is associated with relapse of tuberculosis even after adjustment for the socioeconomic variables. Smoking cessation support should be incorporated in the strategies to improve effectiveness of Tuberculosis Control Programs.

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“…Segundo dados da World Health Organization -WHO (1997), um terço da população mundial está infectada pelo Mycobacterium tuberculosis. A tuberculose é a doença infecciosa que mais mata, correspondendo a 25% do total de óbitos evitáveis nos países em desenvolvimento 11 .…”

Section: Introductionunclassified

Avaliação dos sintomáticos respiratórios no Pronto-Socorro do Hospital das Clínicas da FMUSP: baixo índice de suspeita de tuberculose pulmonar

Sano

Félix

Mentone

et al. 2001

Rev. Med. (São Paulo)

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Pela importância do diagnóstico precoce da tuberculose pulmonar, a Organização Mundial de Saúde (OMS)preconiza a investigação de todos os sintomáticos respiratórios através da baciloscopia de escarro. Objetivo: Determinara porcentagem de sintomáticos respiratórios investigados com baciloscopia de escarro no PS-ICHC. Métodos: Foirealizado um estudo transversal revisando todos os atendimentos do PS-ICHC em fevereiro/2000, sendo identificados os sintomáticos respiratórios (tosse produtiva por 3 semanas ou mais). Determinamos, através da ficha clínica e do laboratório, a porcentagem desses pacientes investigados com baciloscopia de escarro. Resultados: Foram selecionadas 55 das 14.780 fichas avaliadas. Entre os 52 sintomáticos respiratórios, foi solicitada baciloscopia de escarro para apenas 9 (16,4%). Desses, 3 tinham tuberculose (33,3%). Conclusão: Apesar da recomendação da OMS, apenas 16,4% dos sintomáticos respiratórios foram investigados com baciloscopia de escarro na amostra estudada do PS- ICHC.

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Interação de fatores riscos em tuberculose

Cited by 4 publications

References 2 publications

A case control study of risk factors associated with pulmonary tuberculosis in Romania: Experience at a clinical hospital of pneumology

A case control study of risk factors associated with pulmonary tuberculosis in Romania: Experience at a clinical hospital of pneumology

Smoking increases the risk of relapse after successful tuberculosis treatment

Avaliação dos sintomáticos respiratórios no Pronto-Socorro do Hospital das Clínicas da FMUSP: baixo índice de suspeita de tuberculose pulmonar

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