The present study is an attempt to measure the morphological parameters of the three famous Annona varieties grown in Egypt, and study the nutritional value, bioactive compounds and phenolic compounds of the Annona fruits. Concerning the morphological parameters Abdel Razek variety had the highest fruit weight (621.43 g) and fruit peel weight (121.94 g), while Balady variety fruits have the highest ratio of fruit peel to the total fruit weight (0.289) and the number of seeds in one fruit (55). Hindi variety recorded the highest weight values of 100 seed (11.74 g). It was found that the highest levels of fats, fiber, carbohydrates, most quantitative sugar and TSS were recorded in the Abd El-Razik variety. The highest contents of moisture, ash and protein were recorded in the Hindy variety. While the acidity content was nearly the same in the three varieties. Abdel Razek variety was the highest compared with the other varieties in all the estimated mineral elements (P, K, Fe, Ca, Zn and Mg). Abde Razik verity was high in bioactive compounds as ascorbic acid, flavonoid, and antioxidant activity, while Hindy variety was the highest in phenolics and DPPH.