Estudo experimental da resposta tecidual à presença de celulose produzida por Acetobacter xylinum no dorso nasal de coelhos

Amorim, Wander Lopes; Costa, Henrique Olival; Souza, Flávia Coelho de; Castro, Marí­lia Germanos de; Silva, Leonardo da

doi:10.1590/s0034-72992009000200008

Cited by 4 publications

(4 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…e. Reconstructive / aesthetic surgery [14] Ideal for nasal reconstruction. The response of tissue in the presence of nanocellulose in nose bone was evaluated.…”

Section: Nanocellulose For Biomedical Usementioning

confidence: 99%

Cellulose - Chitosan Nanocomposites - Evaluation of Physical, Mechanical and Biological Properties

Riva¹,

García-Estrada²,

Vega³

et al. 2015

Cellulose - Fundamental Aspects and Current Trends

View full text Add to dashboard Cite

This research describes the preparation of membranes with chitosan (CS) as the polymeric matrix and cellulose nanocrystals (CNC) as reinforcement. The aim was to evaluate their physical, mechanical and biological properties, and to determine their potential for biomedical use. Membranes were prepared via casting CNC suspensions in CS solution, at CNC concentrations of 0.5%, 1.0% and 2.0% (w/w) with pure chitosan as a reference. Analysis of membrane properties was performed using several techniques, such as ATR-FTIR, SEM, swelling test, maximum water absorption, dynamical mechanical analysis and in vivo (Winstar rats) biocompatibility and biodegradability assays for biological evaluation. Experimental results established that CNC reduced swelling rates and increased the maximum water absorption when CNC concentration was higher. Therefore, the presence of CNC in the matrix reduced Young's modulus by approximately 50% in comparison with pure chitosan. All formulations demonstrated biocompatibility and biodegradability values ranged between 4% and 21% in the 30 days after implantation. Based on these results, these membranes may be of use for biomedical applications.

show abstract

“…e. Reconstructive / aesthetic surgery [14] Ideal for nasal reconstruction. The response of tissue in the presence of nanocellulose in nose bone was evaluated.…”

Section: Nanocellulose For Biomedical Usementioning

confidence: 99%

Cellulose - Chitosan Nanocomposites - Evaluation of Physical, Mechanical and Biological Properties

Riva¹,

García-Estrada²,

Vega³

et al. 2015

Cellulose - Fundamental Aspects and Current Trends

View full text Add to dashboard Cite

show abstract

“…Secondly, the material/device should be studied to ensure its properties function as they were designed. 3,11 The host response to biomaterials has been studied for decades. 11,28,29 Recently, there has been particular interest in the quest to finding a tech-nical solution of obliterating the LAA, by inserting a device with biocompatible materials within the human body.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Local Tissue Reaction After the Application of a 3D Printed Novel Holdfast Device for Left Atrial Appendage Exclusion

et al. 2019

View full text Add to dashboard Cite

The left atrial appendage (LAA) is a small, fingerlike extension of the left atrium and its exclusion is used as a treatment strategy to prevent ischemic stroke. Existing holdfast devices may damage the tissue, are unisized and not adjustable. A novel holdfast device for LAA exclusion devoid of these shortcomings was designed and 3D-printed using the Selective Laser Sintering (SLS) technology with polyamide powder and tested it on animal model. We selected the SLS 3D printing technology due to its wid14e availability and low production costs which could provide on-site 3D printing for specific patient. The purpose of this study was to evaluate the biocompatibility of the reported holdfast device and compare the histological results obtained for local tissue reactions to those obtained for an established grafting material. Thirty swine subdivided into two groups were examined. The LAA exclusion device was implanted and was either coated with a polyester vascular implant or not coated at all and the histological response to the device's presence was evaluated which is a standard approach to test the device biocompatibility. In all cases, complete occlusion was seen without any pathological findings during the incubation time. In both groups, the surface of the atrium under a holdfast device was smooth and shiny and had no clots. The foreign body reaction of the LAA holdfast device made of polyamide powder was insignificantly lower compared to the polyester graft. Thus, it fulfils the parameters of biocompatibility at the highest degree, and makes it suitable material for the manufacturing of LAA holdfast devices.

show abstract

“…Studies on the impact of BC membranes on bone regeneration on rat skulls produced results that were equivalent, showing that after 8 weeks of implantation, new bone had formed on both the periphery and the core of the bone defect [74]. The study of bacterial cellulose membranes as a barrier membrane for directed bone regeneration on rat calvarial defects did not cause an inflammatory reaction and preserved appropriate spaces for bone regeneration [75], and no signs of a foreign body reaction were noticed when bacterial cellulose grafts were utilized to treat rabbit nasal dorsum, which fragmented in six months, a favorable sign of bacterial cellulose integration [76]. At day 14 after implant, mineralized formation of bones was seen on the exterior and inner surface of the femoral cortical bone of dogs [77].…”

Section: Applications Of Bacterial Cellulose For Bone Regenerationmentioning

confidence: 99%

Harnessing Natural Polymers for Nano-Scaffolds in Bone Tissue Engineering: A Comprehensive Overview of Bone Disease Treatment

Saurav,

Sharma,

Kumar

et al. 2024

CIMB

View full text Add to dashboard Cite

Numerous surgeries are carried out to replace tissues that have been harmed by an illness or an accident. Due to various surgical interventions and the requirement of bone substitutes, the emerging field of bone tissue engineering attempts to repair damaged tissues with the help of scaffolds. These scaffolds act as template for bone regeneration by controlling the development of new cells. For the creation of functional tissues and organs, there are three elements of bone tissue engineering that play very crucial role: cells, signals and scaffolds. For the achievement of these aims, various types of natural polymers, like chitosan, chitin, cellulose, albumin and silk fibroin, have been used for the preparation of scaffolds. Scaffolds produced from natural polymers have many advantages: they are less immunogenic as well as being biodegradable, biocompatible, non-toxic and cost effective. The hierarchal structure of bone, from microscale to nanoscale, is mostly made up of organic and inorganic components like nanohydroxyapatite and collagen components. This review paper summarizes the knowledge and updates the information about the use of natural polymers for the preparation of scaffolds, with their application in recent research trends and development in the area of bone tissue engineering (BTE). The article extensively explores the related research to analyze the advancement of nanotechnology for the treatment of bone-related diseases and bone repair.

show abstract

Estudo experimental da resposta tecidual à presença de celulose produzida por Acetobacter xylinum no dorso nasal de coelhos

Cited by 4 publications

References 26 publications

Cellulose - Chitosan Nanocomposites - Evaluation of Physical, Mechanical and Biological Properties

Cellulose - Chitosan Nanocomposites - Evaluation of Physical, Mechanical and Biological Properties

Evaluation of Local Tissue Reaction After the Application of a 3D Printed Novel Holdfast Device for Left Atrial Appendage Exclusion

Harnessing Natural Polymers for Nano-Scaffolds in Bone Tissue Engineering: A Comprehensive Overview of Bone Disease Treatment

Contact Info

Product

Resources

About