Amiloidose com múltiplos focos em trato aéreo-digestivo superior: relato de caso e revisão de literatura

Abstract

Há na literatura inúmeras descrições de amiloidose limitada à laringe, sendo que esta afecção corresponde a cerca de 1% dos tumores benignos da laringe. Entretanto, há somente três relatos de amiloidose acometendo a região do anel de Waldeyer. Descreveremos um raro caso de amiloidose em que há acometimento de sítios distintos do trato aéreo-digestivo superior: pilar amigdaliano, rinofaringe, supraglote e glote, sem continuidade aparente do tecido amilóide. Abordaremos, também, o seguimento pós-operatório com uma disfagia grave.

Laryngeal amyloidosis presenting as false vocal fold bulging: clinical and therapeutic aspects

“…The lesion occurs mainly in the vestibular fold (55%), presenting as subepithelial edema or nodular formation. 1 The diagnosis is rarely suspected and is often only attained after anatomopathological analysis, which discloses typical positive birefringence under polarized light after Congo red staining, showing a greenish color. 5 In the present case, a saccular cyst was suspected, a disease characterized by obstruction/atresia of the laryngeal saccule orifice, with consequent mucus retention and submucosal bulging.…”

“…The larynx is the main affected site in upper aerodigestive tract amyloidosis, which predominates in men in the fifth decade of life 1 , 2 and represents approximately 1% of benign tumors in this organ. 1 Dysphonia is the main symptom 3 , 4 and histopathological diagnosis is the gold standard.…”