Bacteriologia do aspirado do meato médio em pacientes com fibrose cística

Abstract

The combination of factors, such as abnormal viscosity of the paranasal sinus secretions, decreased sinus drainage, and impaired mucociliary clearance may account for the establishment of a suitable and opportune environment for the colonization of bacteria in the paranasal sinuses of patients with cystic fibrosis. Aim: The goal of the present study was to assess the bacteriology of the middle meatus aspirate in patients diagnosed whit cystic fibrosis. Material and Methods: Through a cross-sectional prospective study, a sample consisting of 23 patients evaluated for 2 years, was assessed. Firstly, we established the relationship between the middle meatus culture and the maxillary sinus x-ray. In second, we studied the relationship between the middle meatus aspirate bacteriology and the sputum bacteriology. Results: In total, 42 aspirates of the middle meatus were carried out. In 17 (73.91%) of the 23 patients, the aspirates were negative; and in 6 (26.08%) they were positive. Out of the 42 aspirates,31 (78.8%) were negative, and 11 (26.2%) were positive. The presence of Pseudomonas aeruginosa was observed in 18.18% of the positive cultures, and Staphylococcus aureus was observed in 27.28%. Conclusion:The great majority of the middle meatus aspirates of the patients with cystic fibrosis were negative.

Cystic Fibrosis: Brazilian ENT Experience

“…In this study, no association was found between the genotype and the presence or severity of nasal polyposis [25]. …”

“…Rhinorrhea was reported by only four patients. Franche and coworkers [25] in Porto Alegre, the southeast Brazilian's capital in Rio Grande do Sul state, found only two out of 23 patients with bilateral polyposis and concerning nasal obstruction, nasal secretion, and headache only eight (34.8%) reported nasal obstruction, ten (43,5%) complained of nasal secretion, and none had headache. Weber and Ferrari [26] (Botucatu, Sao Paulo State) evaluated 23 patients with an average age of 6 years and 4 months, and 22% of them complained of oral breathing.…”

“…Boari and Castro Júnior [24] found polyps in only three (8.82%) out of 34 CF patients, from six to twenty-two years of age, evaluated using nasal endoscopy. Franche and coworkers [25] found only two out of 23 patients with bilateral nasal polyps in both cases. Sakano and colleagues [20] identified nasal polyps in 36% of 50 patients, over two years of age, evaluated using rigid endoscopy under general anesthesia, a method that may have allowed more accurate diagnosis of polyps, even small ones.…”

“…Weber and Ferrari [26] classified the polyposes according to the scale by Johansson and colleagues [36]: grade I in four patients (44.4%), grade II in one patient (11.1%), and grade III in four patients (44.4%). Using endoscopy, Franche and coworkers [25] found other significant endoscopic evidence in 23 CF patients. The inferior turbinate was hypertrophic in 34.8%.…”

“…Franche et al [25], from Porto Alegre (Rio Grande do Sul State), analyzed the bacteriology of aspirate from the middle meatus and sputum of 23 patients with CF. The Junh-Tym-Tap aspiration system and a rigid endoscope were used to collect material.…”