Relação entre as complicações hemorrágicas pós cirúrgicas e o volume das tonsilas palatinas

Brasileiro, Hélio; Lee, Isabelle W. C. Cunha; Rapoport, Abrão

doi:10.1590/s0034-72992004000100010

Cited by 1 publication

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References 14 publications

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“…The method was also considered low cost and easily employed, and it is rare that suture or ligature of the vessels in the region is needed. 8 When we compared the degree of inflammation between the experimental and control groups, we noted that there was no significant difference. The same was observed in a study that investigated the inflammatory process with use of bismuth subgallate in partial hepatectomies in rats.…”

Section: Discussionmentioning

confidence: 95%

Avaliação dos efeitos do subgalato de bismuto na proliferação de miofibroblastos

et al. 2016

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Background: Bismuth subgallate is an insoluble heavy metal that is used for its astringent and hemostatic properties. Objective: To evaluate the effects of bismuth subgallate on the healing process by observation of myofibroblasts in the skin of rats. Methods: A sample of 60 Wistar rats was used. Each rat was subjected to a dorsal skin wound and allocated to one of two groups: a control group, in which 0.9% sodium chloride was administered daily, or an experimental group, in which 0.5 mg of bismuth subgallate was administered daily. Each of these groups was further subdivided into three subsets, which were reoperated after 3, 7 and 14 days respectively for excision and collection of the skin wound specimens. Samples were treated with hematoxylin eosin, picrosirius, and immunohistochemical staining to enable assessment of myofibroblast counts, inflammatory response phase, and collagen synthesis. Results: No inflammatory process differences were detected between the control and experimental groups at 3 days (p = 1), 7 days (p = 0.474), or 14 days (p = 303). Evaluation of types I and III collagen in the control group did not demonstrate healing benefits at 3 days (p = 0.436), 7 days (p = 0.853), or 14 days (p = 0.436); whereas in the experimental group there were increases in types I and III collagen at 3 and 14 days (p = 0.005). Immunohistochemical analysis confirmed the results of hematoxylin eosin staining, since there were no differences between subsets in terms of area of myofibroblasts, in the experimental (p = 0.4) or the control (p = 0.336) groups. Conclusions: Administration of bismuth subgallate to skin wounds in rats did not result in any evidence of benefits to healing, i.e., no difference in fibroplasia was detected when experimental and control groups were compared.

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Section: Discussionmentioning

confidence: 95%

Avaliação dos efeitos do subgalato de bismuto na proliferação de miofibroblastos

et al. 2016

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Relação entre as complicações hemorrágicas pós cirúrgicas e o volume das tonsilas palatinas

Abstract: Palavras-chave: tonsilectomia, hemorragia, hipertrofia das tonsilas palatinas.

Cited by 1 publication

References 14 publications

Avaliação dos efeitos do subgalato de bismuto na proliferação de miofibroblastos

Avaliação dos efeitos do subgalato de bismuto na proliferação de miofibroblastos

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