Contribuição ao estudo da lagoquilascaríase humana

Abstract

Objetivo: realiza análise bibliográfica comentada sobre lagoquilascaríase humana, relativa ao período de 1909 a 2001. Introdução: Trata-se de zoonose causada por Lagochilascaris, com 109 casos humanos registrados exclusivamente na América Tropical, destacando-se o Estado do Pará com 49,5% da casuística mundial. Forma de estudo: prospectivo. Material e método: Utiliza como metodologia consulta a um guia de referência e a discos de 14 bases de dados; pesquisa direta a 8 bibliotecas; nos acervos bibliográficos de Fraiha e Leão, e na bibliografia dos trabalhos obtidos através destas fontes. Conclusão: Justifica o presente estudo pela dispersão e escassez de informações sobre o tema, muitas vezes inexistentes nos bancos de dados; e pelo aumento da casuística humana registrada nas últimas décadas, predominantemente na Amazônia.

Lagochilascaris minor Leiper, 1909 (Nematoda: Ascarididae) in Mexico: three clinical cases from the Peninsula of Yucatan

“…Human lagochilascariasis (HL) is a zoonosis caused by Lagochilascaris minor Leiper 1909 which also can be found in cats and dogs 1 . HL is considered an emerging zoonosis in the Americas, spreading from Mexico to Argentina and the Caribbean Islands 8 . HL is common in people living in slums and especially people from rural areas 5 .…”

“…The life cycle of L. minor is still unclear; eggs, larvae, and adult worms have all been found on lesions in both animals and humans 8 . A heteroxene cycle has been proposed after various studies with experimental models with rodents as intermediary hosts, since the parasite's development stops at the third stage larvae (L3) and turns into a cyst form.…”

Lagochilascariasis leading to severe involvement of ocular globes, ears and meninges

“…It is an emergent helminthiasis, often chronic and sometimes fatal 8,13,17 . There are about 110 reported cases in the literature 9,15 but only one, published in 1926, described an ocular globe involvement similar to this case 16 . In recent years, however, there has been an increase in the number of cases, but many of them were neither notified nor published.…”

“…Proteolytic enzymes can facilitate invasion, migration, evasion from immune response, nutrition and parasite development in the host 1 . A chronic granulomatous disease progressively develops in these regions 15,18 . Osteolysis is a prominent feature that enables the parasite to migrate further.…”

“…Osteolysis is a prominent feature that enables the parasite to migrate further. Intermittent elimination of the parasite through lesion orifices, ears, mouth, and nose is frequent, and in most cases is the main clue for the diagnosis 15,21 . However, its absence must not rule out the possibility of lagochilascariasis, as seen in this case.…”