Retinopatia de Purtscher e Purtscher-like

Abstract

RESUMOA retinopatia de Purtscher é uma condição caracterizada pela baixa súbita de acuidade visual precedida por traumatismo, principalmente torácico, podendo aparecer em outros tipos de traumatismos. Uma entidade com o mesmo quadro clínico descrita como retinopatia "Purtscher-like" apresenta características semelhantes, no entanto na inexistência de um trauma direto. Neste caso pode vir associada a fenômenos tromboembólicos, secundária a pancreatite aguda, pós-manobra de Valsalva, pós-anestesia retrobulbar, e outros. O achado oftalmológico comum é a presença de manchas esbranquiçadas no polo posterior com hemorragias peripapilares, associadas à papiledema e áreas de não perfusão capilar. Neste artigo, revisamos os critérios diagnósticos, os padrões nos exames complementares e tratamentos utilizados em cada caso.

Severe ocular alteration associated with fracture of the scapula. Case report

“…Although its association with fatty thromboembolism is irrefutable, this disease was initially correlated with vascular lesions due to severe cranial trauma. However, more recently, it has been described in association with injuries due to air bags and the practice of bungee jumping 7 …”

“…From ocular fundoscopy, the retina is characterized by cotton-wool stains, edema and macula associated with superficial hemorrhage 7, 8. The consensus is that fatty emboli are formed and lead to arteriolar occlusion and consequently to infarction of the microvasculature in the retinal nerve fiber layer.…”

A benzene-mapping approach for uncovering cryptic pockets in membrane-bound proteins

“…Flaviviruses are a family of enveloped, single-stranded RNA viruses that include a range of vector-borne human pathogens such as DENV, Zika virus, yellow fever virus, or Japanese and tick-borne encephalitis virus 31 . These viruses present a major health burden on a global scale, especially since climate change is expanding the range of virus-carrying mosquitoes previously contained predominantly to the tropical region 32,33 . DENV, in particular, is responsible for 390 million cases worldwide, 96 million of which are symptomatic 34 .…”

Hemorrhagic retinopathy in an infant with hemolytic-uremic syndrome

“…Purtscher's retinopathy was first described in 1910 by Otmar Purtscher as whitish lesions with hemorrhagic retinopathy associated with low visual acuity secondary to a fall (8) . From 1975 Inkles introduced the term Purtscher-like retinopathy to describe the same clinical feature in a case of pancreatitis with no history of previous trauma (8) . Ever since these terms are used to describe the fundus changes as peripapillary cotton wool spots, intraretinal hemorrhages and Purtscher fleckens.…”