Uso de sugamadex após reversão incompleta com neostigmine do bloqueio neuromuscular induzido por rocurônio

Abstract

Summary: Menezes CC, Peceguini LAM, Silva ED, Simões CM -Use of Sugammadex after Neostigmine Incomplete Reversal of RocuroniumInduced Neuromuscular Blockade.Background and objectives: Neuromuscular blockers (NMB) have been used for more than half of a century in anesthesia and have always been a challenge for anesthesiologists. Until recently, the reversal of nondepolarizing neuromuscular blockers had only one option: the use of anticholinesterase agents. However, in some situations, such as deep neuromuscular blockade after high doses of relaxant, the use of anticholinesterase agents does not allow adequate reversal of neuromuscular blockade. Recently, sugammadex, a gamma-cyclodextrin, proved to be highly effective for reversal of NMB induced by steroidal agents.