Anestesia espinhal com 10 mg de bupivacaína hiperbárica associada a 5 µg de sufentanil para cesariana: estudo de diferentes volumes

Raquianestesia em operação cesariana. Emprego da associação de bupivacaína hiperbárica (10 mg) a diferentes adjuvantes

“…Incidence of hypotension in all four groups was lower than that reported in literature and controlled by displacing the uterus to the left, volume expansion, and intravenous ephedrine -strategies used for preventing hypotension associated with spinal anesthesia [14][15][16] . Thus, in all four groups, newborns showed no signs of fetal distress, evidenced by Apgar scores between 8 and 10 at 5 and 10 minutes, respectively, which confirmed the safety of the product in the conceptual combination of drugs studied, results similar to those described in literature 2,3,23,27 .…”

“…However, the major factor triggering the incidence of hypotension associated with spinal anesthesia (50% to 85%) in cesarean section is the local anesthetic dosage, along with other factors such as oxytocin infusion and those involved in cephalad spread of local anesthetics in cerebrospinal fluid [14][15][16][17] .…”

A Randomised Controlled Trial to Evaluate the Effectiveness of Intrathecal Bupivacaine Combined with Different Adjuvants (Fentanyl, Clonidine and Dexmedetomidine) in Caesarean Section

“…The incidence of hypotension in all 4 groups was lower than that reported in previous studies and was controlled by using strategies for prevention hypotension associated with spinal anesthesia which included displacing the uterus to the left, volume expansion, and intravenous ephedrine [39,40]. Therefore, the new-borns in all groups showed no signs of fetal distress, supported by Apgar scores between 8 and 10 at 1 and 10 min, respectively.…”

Spinal anesthesia for elective cesarean section. Bupivacaine associated with different doses of fentanyl: randomized clinical trial

“…Although the relationship between the occurrence of pruritus and the dose of fentanyl is not sufficiently evident, it has been a frequent complaint among patients who received this drug intrathecally. 1 , 6 , 10 , 11 , 12 , 13 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 Approximately 80% of patients receiving fat-soluble opioid intrathecally report pruritus, which in some cases is described as severe and stressful. 27 , 28 , 29 , 30 In this study, the occurrence of pruritus was similar in the groups receiving different doses of fentanyl, therefore, it was not a dose-dependent effect as described by many authors.…”

“… 3 , 10 In the doses used, fentanyl did not change the vitality of newborns, confirmed by Apgar score above 7 in the 1 st and 5 th minutes, results previously observed, and that confirm the safety of the association of drugs used. 10 , 17 , 20 , 23 …”