Dr. Valdir Cavalcanti Medrado

Anti-inflammatory and Antinociceptive Activity of Epiisopiloturine, an Imidazole Alkaloid Isolated from Pilocarpus microphyllus

“…The inflammatory process involves a complex cascade of biochemical and cellular events that occur in response to cellular injury . This process triggers formation of inflammatory neuromediators that activate nociceptors when released, facilitating pain transmission and peripheral inflammatory responses .…”

“…This process triggers formation of inflammatory neuromediators that activate nociceptors when released, facilitating pain transmission and peripheral inflammatory responses . Although a large number of analgesics and anti-inflammatory agents are currently in clinical use, it would be useful to identify novel drugs having a wider specificity and lower toxicity than those currently available …”