Padronização da anestesia em suínos para procedimentos cirúrgicos cardiovasculares experimentais

Abstract

An adequate plane of anesthesia for the proposed procedure was achieved.

10.1538/expanim.63.423

“…In fact, it has been proved that somatic reflexes could be ineffective to adequately establish the depth of surgical anaesthesia in swine [ 60 ]. Also the corneal-palpebral reflexes is not a good indicator for evaluating the depth of anaesthesia, being it often absent during anaesthesia and even weak in deep sedation [ 13 , 25 , 26 , 58 ]. Therefore, we did not evaluate somatic reflexes during the surgery sessions.…”

“…In addition, the role of swine as a model employed in training for basic surgical techniques and for innovative procedures, such as new laparoscopy devices application, has also to be highlighted [ 32 , 53 ]. In fact, even though the research and training in pigs may present management and logistic complexity compared to small laboratory animals, the importance of these training procedures in swine has been broadly confirmed during the last decade [ 2 , 13 , 26 , 32 , 33 , 46 ].…”

“…Even though the state-of-art of human anaesthesia has reached significant levels and it is continuously developing, the knowledge of swine anaesthesia in subjects undergoing surgery for medical research intents appears to be quite static [ 3 , 60 ]. Furthermore, as an increasing employment of swine for experimental studies and medical training, it seems to be necessary to investigate new and effective anaesthetic protocols for preserving animal welfare in medical investigation and concurrently improving the quality of research [ 2 , 13 , 26 , 33 , 46 ].…”

Influência Do Compost Barn No Conforto E No Bem-Estar De Vacas Leiteiras

“…O autor relatou que com o isofluorano não causa alterações significativas nas variáveis fisiológicas de suínos e o bloqueador neuromuscular reduziu a pressão de CO2 arterial. Dessa forma, é possível considerar que o uso do opioide é viável para garantir protocolos de anestesia balanceada em suínos.Para avaliar injúria isquêmica e de reperfusão em suínos, Simon et al,(2008) optaram por utilizar cetamina (1-2 mg/kg) pela via intramuscular e remifentanil (15-20 mcg/kg/h) pela via intravenosa e em infusão contínua Geovanini et al (2008). administraram a associação de cetamina e midazolam e posteriormente aplicaram a lidocaína para realizar a anestesia local a fim de realizar traqueostomia e obter acesso venoso e arterial em suínos.…”

The Use of a Plastic Guide Improves the Safety and Reduces the Duration of Endotracheal Intubation in the Pig

“…Another obstacle for successful endotracheal intubation of mature pigs, except for minipigs, is the length of the blade of commercially available laryngoscopes: the blades, even with an attached light source, were not long enough to visualize the epiglottis and the laryngeal opening in order to enable safe and successful insertion of endotracheal tube. These anatomical obstacles and technical difficulties have led to the abandonment of the standard orotracheal method of endotracheal intubation method and the use of tracheotomy to endotracheally intubate pigs [2]. In this report, we describe the use of plastic vascular catheter for the safe and successful first-time endotracheal intubation of pigs.…”