Preparação, caracterização e avaliação in vitro de microesferas de bupivacaína em excesso enantiomérico de 50% (S75-R25)

In semi-fine histologic sections, no regular homogeneous distribution of collagen fibers in the endoneurium or degenerative changes of axons and myelin sheaths were observed. In ultrathin sections, we found myelinated axons and normal Remak fibers with axoplasm showing homogeneous distribution of neurofilaments and microtubules. Histomorphometric analysis of axons revealed no significant difference between the axon diameters of the studied groups.

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Assessing the Quality of Random Clinical Anesthesiology Trials Published on the Brazilian Journal of Anesthesiology from 2005 to 2008

Barbosa

Júca

2009

Brazilian Journal of Anesthesiology

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Preparação, caracterização e avaliação in vitro de microesferas de bupivacaína em excesso enantiomérico de 50% (S75-R25)

Abstract: Manufacturing of 50% enantiomeric excess bupivacaine-loaded microspheres by the spray-dryed method with results similar to bupivacaine-loaded microspheres can be done.

Cited by 5 publications

References 9 publications

Assessing the Use of 50% Enantiomeric Excess Bupivacaine-Loaded Microspheres after Sciatic Nerve Block in Rats

Assessing the Use of 50% Enantiomeric Excess Bupivacaine-Loaded Microspheres after Sciatic Nerve Block in Rats

Analysis of the Acute Cytotoxic Potential of Bupivacaine and 50% Enantiomeric Excess Bupivacaine (S75-R25) Incorporated into Microspheres in Rat Sciatic Nerves

Assessing the Quality of Random Clinical Anesthesiology Trials Published on the Brazilian Journal of Anesthesiology from 2005 to 2008

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