Uso do azul de metileno no tratamento de choque anafilático durante anestesia: relato de caso

Stocche, Renato Mestriner; Garcia, L; Reis, Marlene Paulino dos; Klamt, Jyrson Guilherme; Évora, Paulo Roberto Barbosa

doi:10.1590/s0034-70942004000600010

Cited by 14 publications

(3 citation statements)

References 9 publications

(19 reference statements)

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“…Overall, 39 reports were found to be relevant to the research question. Of these, 3 were randomized controlled trials [11], [12], [13], 5 were prospective studies [14], [15], [16], [17], [18], 4 were case reports [10], [19], [20], [21], 25 were retrospective (registry) studies [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], and 2 were meta-analyses [47], [48].…”

Section: Methodsmentioning

confidence: 99%

Risk factors for perioperative complications in inguinal hernia repair – a systematic review

Weyhe

Tabriz

Sahlmann

et al. 2017

Innovative Surgical Sciences

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Abstract:The current literature suggests that perioperative complications occur in 8%-10% of all inguinal hernia repairs. However, the clinical relevance of these complications is currently unknown. In our review, based on 571,445 hernia repairs reported in 39 publications, we identified the following potential risk factors: patient age, ASA score, diabetes, smoking, mode of admission (emergency vs. elective surgery), surgery in low resource settings, type of anesthesia, and (in men) bilateral and sliding hernias. The most commonly reported complications are bleeding (0.9%), wound infection (0.5%), and pulmonary and cardiovascular complications (0.2%). In 3.9% of the included publications, a reliable grading of the reported complications according to Clavien-Dindo classification was possible. Using this classification retrospectively, we could show that, in patients with complications, these are clinically relevant for about 22% of these patients (Clavien-Dindo grade ≥ IIIa). About 78% of all patients suffered from complications needing only minor (meaning mostly medical) intervention (Clavien-Dindo grade < III). Especially with regard to the low incidence of complications in inguinal hernia repair, future studies should use the Clavien-Dindo classification to achieve better comparability between studies, thus enabling better correlation with potential risk factors.

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Section: Methodsmentioning

confidence: 99%

Risk factors for perioperative complications in inguinal hernia repair – a systematic review

Weyhe

Tabriz

Sahlmann

et al. 2017

Innovative Surgical Sciences

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“…A number of case reports describe use of methylene blue for the treatment of refractory anaphylaxis [202][203][204][205][206]. Methylene blue may prevent PAF-mediated anaphylaxis by blocking nitric oxide (NO)-mediated vascular smooth muscle relaxation [207].…”

Section: Treatmentmentioning

confidence: 99%

Anaphylaxis: mechanisms and management

Lee

Vadas

2011

Clinical &Amp; Experimental Allergy

115

101

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Anaphylaxis is a serious allergic reaction that can be rapid in onset and occasionally fatal. This is a review of the literature on the epidemiology of anaphylaxis, diagnostic criteria, mechanisms, and management. This current review of the literature is intended for clinicians, trainees, and researchers as a comprehensive review of anaphylaxis with a focus on incorporating the latest advances in the field.

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“…MB has bacteriostatic, antiviral and antifungal effects and acts on vascular musculature. 20,21 Additionally, MB, when excited by red light, produces oxygen "singlet". Still, it presents the advantage of being low cost, easy to acquire and causes little damage to the patient.…”

Section: Introductionmentioning

confidence: 99%

Photodynamic Therapy for the Treatment of American Tegumentary Leishmaniasis: Evaluation of Therapies Association in Experimentally Infected Mice With Leishmania (Leishmania) amazonensis

et al. 2018

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Introduction: American tegumentary leishmaniasis (ATL) is a zoonotic disease caused by protozoan parasites of the genus Leishmania that affects the skin and mucous membrane. Currently, the available drugs for the treatment are injectable, with side effects, long-term treatment regimen and there is the possibility of drug resistance. Thus, alternative therapies have been tested, including photodynamic therapy (PDT). We evaluated the efficacy of PDT on its own and associated with the prescribed ATL treatment. Methods: BALB/c mice were infected with Leishmania (Leishmania) amazonensis and divided into 6 groups: Gluc+PDT, treated with Glucantime® and photodynamic therapy (PDT) with methylene blue (MB)/red LED (light-emitting diode); Gluc, treated with Glucantime®; PDT, treated with PDT with MB/red LED; Ampho+PDT, treated with amphotericin and PDT with MB/red LED; Ampho, treated with amphotericin; and control, which were infected but not treated. Two treatment cycles were performed. After 165 days of infection, the parasite load was determined. Results: Statistical differences were not found (P>0.05) between measures of volume and thickness of the infected footpads in the treated groups when compared with the control group. However, there was a significant reduction (P<0.05) in the parasitic load of the popliteal lymph nodes of the Gluc+PDT, Gluc, PDT and Ampho groups when compared to the control group. In the histological analysis of the infected footpads, the Gluc+PDT group presented a smaller amount of amastigote nests and lower intensity of the mononuclear infiltrate when compared to the Gluc and PDT groups. Conclusion: The results showed that although there is no significant difference in the evaluations of footpad size (thickness and volume), there is a downward measurement tendency in the Gluc+PDT group, as it can be observed by volume data and corroborated by parasite negative load.

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Uso do azul de metileno no tratamento de choque anafilático durante anestesia: relato de caso

Cited by 14 publications

References 9 publications

Risk factors for perioperative complications in inguinal hernia repair – a systematic review

Risk factors for perioperative complications in inguinal hernia repair – a systematic review

Anaphylaxis: mechanisms and management

Photodynamic Therapy for the Treatment of American Tegumentary Leishmaniasis: Evaluation of Therapies Association in Experimentally Infected Mice With Leishmania (Leishmania) amazonensis

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