2004
DOI: 10.1590/s0034-70942004000400016
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Lesão neurológica em cirurgia cardíaca: aspectos fisiopatológicos

Abstract: A lot has been said about cognitive function disorders after heart surgeries, such as myocardial revascularization, which are present causes of increased morbidity and mortality, in addition to longer hospital stay. Major advances to decrease such rates have been observed in this field, and others are still expected aiming at neurological injuries prevention.

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Cited by 10 publications
(16 citation statements)
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“…Similarly, SAH and antihypertension therapy may be related to the cognitive outcome (Table 1), a reflection of the impaired self-regulation of the cerebral blood flow, hardening of the small cerebral arteries and generalized atherosclerotic disease existent in hypertensive individuals. Kadoi & Goto [19] Ille et al [20] Newman et al [3] Di Carlo et al [21] Ho et al [22] Roach et al [23] Wolman et al [24] Selnes et al [25] Kadoi & Goto [19] Nötzold et al [26] Intra-operative factors a) Embolization The formation of emboli, whose genesis would be the atheroma of the aortic wall, aggregated platelets, air bubbles originating from the oxygenator and the heart chambers may be the main cause of encephalic injury and the deterioration of pre-existent lesions [8]. These are subdivided in micro and macroemboli, with the former being more relevant in the emergence of CD.…”
Section: C) Previous Diseasesmentioning
confidence: 99%
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“…Similarly, SAH and antihypertension therapy may be related to the cognitive outcome (Table 1), a reflection of the impaired self-regulation of the cerebral blood flow, hardening of the small cerebral arteries and generalized atherosclerotic disease existent in hypertensive individuals. Kadoi & Goto [19] Ille et al [20] Newman et al [3] Di Carlo et al [21] Ho et al [22] Roach et al [23] Wolman et al [24] Selnes et al [25] Kadoi & Goto [19] Nötzold et al [26] Intra-operative factors a) Embolization The formation of emboli, whose genesis would be the atheroma of the aortic wall, aggregated platelets, air bubbles originating from the oxygenator and the heart chambers may be the main cause of encephalic injury and the deterioration of pre-existent lesions [8]. These are subdivided in micro and macroemboli, with the former being more relevant in the emergence of CD.…”
Section: C) Previous Diseasesmentioning
confidence: 99%
“…There are three main causes for the genesis of microbubbles: the oxygenator itself, the cooling process of gasses which alters their solubility with predisposition to the formation of bubbles in the blood stream and the opening of heart chambers during the surgical procedure [8].…”
Section: C) Previous Diseasesmentioning
confidence: 99%
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