Avaliação do hiperinsulinismo em amostra de crianças pré-puberes

Abstract

Objectives: To determine the relationship between body mass index (BMI), homeostasis model assessment -insulin resistance (HOMA-IR) and insulinemia.Methods: This was a prospective cross-sectional observational study of 132 prepubescent schoolchildren residents in the municipality of Santo André, Brazil. Children underwent anthropometric assessment, their glycemia and insulinemia were measured and their HOMA-IR index calculated.Results: Seventy-eight of the 132 children (59.1%) were girls and 54 were boys (40.9%), with a mean age of 8.7 years and mean BMI of 13.7 kg/m 2 . A significant positive association was detected between HOMA-IR and BMI, insulin and BMI, weight and HOMA and between insulin and weight. It was also found that the higher the BMI, the greater the HOMA score. Conclusions:The results of this study allow for the conclusion that there is a strong association between hyperinsulinism and obesity. Measures should be taken to avoid weight gain during childhood and adolescence. No conflicts of interest declared concerning the publication of this article.Suggested citation: Mieldazis SF, Azzalis LA, Junqueira VB, Souza FI, Sarni RO, Fonseca FL. Hyperinsulinism assessment in a sample of prepubescent children.

Comparação Dos Índices Homa-Ir Na Avaliação Da Resistência Insulínica Em Adultos

“…No estudo de Mieldazis et al (2010), os coeficientes de correlação encontrados sugerem uma associação significativa do IMC com a resistência insulínica, o que indica uma relação entre hiperinsulinemia e excesso de peso.…”