Características clínicas e da saturação transcutânea de oxigênio em lactentes hospitalizados com bronquiolite viral aguda

Rubin, Fernanda M.; Fischer, Gilberto Bueno

doi:10.1590/s0021-75572003000500011

Cited by 7 publications

(5 citation statements)

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“…, 4 , 5 As the disease progresses, tachypnea and wheezing may appear, along with increasing respiratory distress and contraction of the respiratory muscles during inspiration 45 In the acute phase, bronchiolitis is often associated with nasal congestion, irritability, and feeding problems 6…”

Section: Introductionmentioning

confidence: 99%

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Sinais clínicos de disfagia em lactentes com bronquiolite viral aguda

Barbosa

Gomes

Fischer

2014

Revista Paulista de Pediatria

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Objective:To determine the occurrence of clinical signs of dysphagia in infants with acute viral bronchiolitis, to compare the respiratory parameters during deglutition, and to ensure the intra- and inter- examiners agreement, as well as to accomplish intra and interexaminators concordance of the clinical evaluation of the deglutition. Methods:This was a cross-sectional study of 42 infants aged 0-12 months. The clinical evaluation was accompanied by measurements of respiratory rate and pulse oximetry. A score of swallowing disorders was designed to establish associations with other studied variables and to ensure the intra- and interrater agreement of clinical feeding assessments. Caregivers also completed a questionnaire about feeding difficulties. Significance was set at p<0.05. Results:Changes in the oral phase (prolonged pauses) and pharyngeal phase (wheezing, coughing and gagging) of swallowing were found. A significant increase in respiratory rate between pre- and post-feeding times was found, and it was determined that almost half of the infants had tachypnea. An association was observed between the swallowing disorder scores and a decrease in oxygen saturation. Infants whose caregivers reported feeding difficulties during hospitalization stated a significantly greater number of changes in the swallowing evaluation. The intra-rater agreement was considered to be very good. Conclusions:Infants with acute viral bronchiolitis displayed swallowing disorders in addition to changes in respiratory rate and measures of oxygen saturation. It is suggested, therefore, that infants displaying these risk factors have a higher probability of dysphagia.

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Section: Introductionmentioning

confidence: 99%

“…, 4 , 5 À medida que a doença progride, podem aparecer taquipneia e sibilância, juntamente com dificuldade respiratória crescente e retração dos músculos respiratórios durante a inspiração 45 na fase aguda, a bronquiolite é frequentemente associada com obstrução nasal, irritabilidade e problemas alimentares 6…”

Section: Introductionunclassified

Sinais clínicos de disfagia em lactentes com bronquiolite viral aguda

Barbosa

Gomes

Fischer

2014

Revista Paulista de Pediatria

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“…Bronquiolite viral aguda (BVA) é a causa mais comum de hospitalização entre lactentes menores de 6 meses de idade nos países desenvolvidos 1 . Em nosso meio, a BVA é igualmente responsável por um expressivo número de hospitalizações em crianças abaixo de 1 ano de idade 2 . O vírus respiratório sincicial (VRS) é considerado o principal agente etiológico da doença 3,4 .…”

Section: Introductionunclassified

Concentrations of interleukin-2 in the nasopharyngeal secretion of children with acute respiratory syncytial virus bronchiolitis

Giugno¹,

Amantéa²,

Barreto³

2004

J Pediatr (Rio J)

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“…1 In our setting, AVB is responsible for a significant number of hospital admissions in infants younger than one year. 2 The respiratory syncytial virus (RSV) is the main etiologic agent of AVB. 3,4 In infants and younger children, RSV causes different levels of infection, from mild upper respiratory infection to severe lower respiratory tract infection.…”

Section: Introductionmentioning

confidence: 99%

“…6 In our setting, results also show a low bronchiolitis-related mortality, but morbidity is significant among previously healthy infants. 2 RSV infections do not provide complete immunity, so reinfections are common throughout life. 7 Children infected with RSV tend to have later episodes of wheezing and asthma.…”

Section: Introductionmentioning

confidence: 99%

Concentrações de interleucina-2 na secreção nasofaríngea de crianças com bronquiolite viral aguda pelo vírus respiratório sincicial

Giugno¹,

Amantéa²,

Barreto³

2004

J. Pediatr. (Rio J.)

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Objective: To assess interleukin-2 concentrations in nasopharyngeal secretion of children (0-24 months) with acute respiratory syncytial virus bronchiolitis, within the first 12 hours of hospital admission, and compare the levels of IL-2 with the severity of the illness.Methods: Prospective study performed between June and August 1999. The study included 62 patients, previously healthy, hospitalized with acute viral bronchiolitis characterized by recent prodromes of coryza and/or nasal obstruction, which evolved to at least two of the following signs: respiratory dysfunction, tachypnea, wheezing or rales, and detection of respiratory syncytial virus in nasopharyngeal aspirate. The nasopharyngeal specimens were collected within 12 hours of hospital admission. The interleukin-2 levels were obtained by enzyme immunoassay. Severity of illness was assessed through oxygen saturation by pulse oximetry, Modified Clinical Score System, time of supplemental oxygen required, length of hospital stay, and mechanical ventilation. Spearman s correlation and Kruskal-Wallis test were used to compared these variables in relation to the median of interleukin-2. The chi-square test was used for categorical analysis of interleukin-2.Results: The mean age of patients was 2.2 (1.3-4) months. Males comprised 54% of cases. Hemoglobin oxygen saturation by pulse oximetry at hospital admission was below 95% in 66.1% of patients. The mean time of supplemental oxygen use was 4.7 days (±3.54). The mean length of hospital stay was 4.25 days (±1.76). Mechanical ventilation was used in 4.8% of patients. The values of interleukin-2 in nasopharyngeal aspirates varied from 0 to 40,256 ng/ml with median of 86 ng/ml (4.4 457.3). The study showed no statistical difference between levels of IL-2 and severity of illness. Conclusions:The interleukin-2 levels showed a heterogeneous behavior. We found no association between interleukin-2 levels in nasopharyngeal secretion and respiratory syncytial virus bronchiolitis.J Pediatr (Rio J). 2004;80(4):315-20: Interleukin-2, acute viral bronchiolitis, respiratory syncytial virus, nasopharyngeal aspirates.

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Características clínicas e da saturação transcutânea de oxigênio em lactentes hospitalizados com bronquiolite viral aguda

Cited by 7 publications

References 20 publications

Sinais clínicos de disfagia em lactentes com bronquiolite viral aguda

Sinais clínicos de disfagia em lactentes com bronquiolite viral aguda

Concentrations of interleukin-2 in the nasopharyngeal secretion of children with acute respiratory syncytial virus bronchiolitis

Concentrações de interleucina-2 na secreção nasofaríngea de crianças com bronquiolite viral aguda pelo vírus respiratório sincicial

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