Juvenile myoclonic epilepsy mimicking focal epilepsy

Sfalsini, Rubia Rasseli; Bassetti, Elida; Alves, José Furtado; Passarelli, Valmir

doi:10.1590/s0004-282x2012001000014

“…Specifically, reductions in processing speed can partially account for age differences in the subjective speed of time (Baudouin, Vanneste, Pouthas, & Isingrini, 2006), age-related decrements in executive functioning may limit future planning (de Paula, Neves, Levy, Nassif, & Malloy-Diniz, 2012), and reductions in working memory capacity may limit the accurate mental simulation of future events (Cole, Morrison, & Conway, 2013). …”

Section: Covariatesmentioning

confidence: 99%

Age Patterns in Mental Representations of Time: Underlying Constructs and Relevant Covariates

Rutt

¹

,

Löckenhoff

²

2016

Experimental Aging Research

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Background/Study Context Research suggests that mental representations of time encompass multiple distinct aspects that vary with age, but prior studies rarely assessed more than one aspect of time perception and did not systematically consider relevant covariates. This lack of integration across studies hampers theory building and limits a deeper understanding of underlying constructs. Methods Five widely used and conceptually distinct measures of time perception (i.e., perceived life position, global future horizons, future orientation and planning, self-continuity, and the temporal extension of episodic future thought) were administered to a demographically stratified adult life-span sample. Theoretically implicated covariates including cognition, current affect, personality, and subjective health were also assessed. Results Principle component analyses suggested a four-component solution. Perceived life position and global future horizons formed a single component reflecting subjective life span; the remaining measures each constituted separate components. The life span component and episodic future thought were negatively associated with age, self-continuity was positively associated with age, and future orientation did not vary by age. Among the covariates, mental and physical health showed the most pronounced associations with time perceptions, but the direction of effects varied across components. Conclusion Findings suggest that mental representations of time encompass multiple components that show distinct age patterns and associations with covariates. Implications for theory building and practical applications are discussed.

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“… 14 In the literature, there are JME cases with an increased frequency of seizures and even diagnosed with treatment-resistant focal epilepsy while being followed up under carbamazepine due to asymmetric or focal EEG findings. 15 …”

Section: Discussionmentioning

confidence: 99%

Isolated Unilateral EEG Findings in Juvenile Myoclonic Epilepsy: A Case Report

Suzgun¹,

Demirbilek²

2022

J Epilepsy Res

0

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Juvenile myoclonic epilepsy (JME) has well-defined clinical and electrophysiological features. On the other hand, large case series have shown that focal and asymmetrical discharges may accompany generalized epileptiform activities in JME. Although it is known that these non-generalized electrophysiological findings do not exclude the diagnosis of this syndrome, some findings may create confusion in the differential diagnosis. In this case report, a case of JME with electroencephalographic findings characterized by isolated unilateral epileptiform activities without typical generalized discharges was discussed. The current case clinically presented with involuntary jerk movements in the bilateral upper extremities. It has been determined that these movements are uni/bilateral myoclonic beats based on home video recordings. Metabolic, toxic and structural problems were excluded in the investigations for the etiology of myoclonus. In the electrophysiological examination performed for epileptic processes, epileptiform discharges localized to the isolated right hemisphere were observed. JME was considered primarily due to clinical findings in the patient, and effective seizure control was achieved in a 4-year follow-up under anti-seizure treatment. The peculiarity of the case is the presence of electrophysiology recordings of isolated unilateral epileptiform activity during the 4-year follow-up period. It should be emphasized that there is no case of JME diagnosed with isolated unilateral epileptiform activity in the absence of generalized spike-slow waves or multiple spike-slow waves in the literature.

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Isolated Unilateral EEG Findings in Juvenile Myoclonic Epilepsy: A Case Report

Suzgun¹,

Demirbilek²

2022

J Epilepsy Res

0

View full text Add to dashboard Cite

Juvenile myoclonic epilepsy (JME) has well-defined clinical and electrophysiological features. On the other hand, large case series have shown that focal and asymmetrical discharges may accompany generalized epileptiform activities in JME. Although it is known that these non-generalized electrophysiological findings do not exclude the diagnosis of this syndrome, some findings may create confusion in the differential diagnosis. In this case report, a case of JME with electroencephalographic findings characterized by isolated unilateral epileptiform activities without typical generalized discharges was discussed. The current case clinically presented with involuntary jerk movements in the bilateral upper extremities. It has been determined that these movements are uni/bilateral myoclonic beats based on home video recordings. Metabolic, toxic and structural problems were excluded in the investigations for the etiology of myoclonus. In the electrophysiological examination performed for epileptic processes, epileptiform discharges localized to the isolated right hemisphere were observed. JME was considered primarily due to clinical findings in the patient, and effective seizure control was achieved in a 4-year follow-up under anti-seizure treatment. The peculiarity of the case is the presence of electrophysiology recordings of isolated unilateral epileptiform activity during the 4-year follow-up period. It should be emphasized that there is no case of JME diagnosed with isolated unilateral epileptiform activity in the absence of generalized spike-slow waves or multiple spike-slow waves in the literature.

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Juvenile myoclonic epilepsy mimicking focal epilepsy

Cited by 3 publications

References 4 publications

Age Patterns in Mental Representations of Time: Underlying Constructs and Relevant Covariates

Age Patterns in Mental Representations of Time: Underlying Constructs and Relevant Covariates

Isolated Unilateral EEG Findings in Juvenile Myoclonic Epilepsy: A Case Report

Isolated Unilateral EEG Findings in Juvenile Myoclonic Epilepsy: A Case Report

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