Validity of the Brazilian version of the freezing of gait questionnaire

Baggio, Jussara Almeida de Oliveira; Curtarelli, Mônica B.; Rodrigues, Guilherme; Tumas, Vítor

doi:10.1590/s0004-282x2012000800008

Cited by 31 publications

(42 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our findings confirm some correlations previously reported between FOG and PD duration and between severity and motor and nonmotor symptoms, thus reinforcing the consistency of these pilot findings. [5][6][7][8][9][10]23 We observed no correlations with other dopa-responsive symptoms such as bradykinesia and rigidity, possibly because our patients underwent assessment in the on state. Conversely, tremor was inversely correlated with FOG, suggesting that both symptoms may have different mechanisms.…”

Section: Discussionmentioning

confidence: 99%

“…3,4 A few factors related to FOG have been identified, including male sex, severity of PD, lower cognitive performance, longer disease duration, higher depression scores, higher doses of dopaminergic medications, motor complications, and lower tremor scores. [5][6][7][8][9][10] Relationships of FOG with health-related quality of life and pharmacological factors, including exposure to dopaminergic and nondopaminergic antiparkinsonian medication and changes in the on or the off state have been poorly explored. The objective of this study was therefore to assess the prevalence of FOG and its relationship with quality of life and to determine the clinical and pharmacological factors related to its occurrence in a large French cohort of ambulatory PD patients.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Prevalence, Determinants, and Effect on Quality of Life of Freezing of Gait in Parkinson Disease

et al. 2014

View full text Add to dashboard Cite

IMPORTANCE Freezing of gait (FOG) is a common axial symptom of Parkinson disease (PD). OBJECTIVE To determine the prevalence of FOG in a large group of PD patients, assess its relationship with quality of life and clinical and pharmacological factors, and explore its changes from the off to on conditions in patients with motor fluctuations. DESIGN, SETTING, AND PARTICIPANTS Cross-sectional survey of 683 patients with idiopathic PD. Scores for FOG were missing in 11 patients who were not included in the analysis. Patients were recruited from referral centers and general neurology clinics in public or private institutions in France. EXPOSURE Patients with FOG were identified as those with a score of 1 or greater on item 14 of the Unified Parkinson's Disease Rating Scale (UPDRS) in the on condition. Item 14 scores for FOG in the off condition were also collected in patients with fluctuating motor symptoms. MAIN OUTCOMES AND MEASURES Quality of life (measured by the 39-item Parkinson's Disease Questionnaire and 36-Item Short Form Health Survey), anxiety and depression (Hospital Anxiety and Depression Scale), clinical features (UPDRS), and drug consumption. RESULTS Of 672 PD patients, 257 reported FOG during the on state (38.2%), which was significantly related to lower quality of life scores (P < .01). Freezing of gait was also correlated with longer PD duration (odds ratio, 1.92 [95% CI, 1.28-2.86]), higher UPDRS parts II and III scores (4.67 [3.21-6.78]), the presence of apathy (UPDRS item 4) (1.94 [1.33-2.82]), a higher levodopa equivalent daily dose (1.63 [1.09-2.43]), and more frequent exposure to antimuscarinics (3.07 [1.35-6.97]) (logistic regression). The FOG score improved from the off to on states in 148 of 174 patients with motor fluctuations (85.1%) and showed no change in 13.8%. The FOG score improved by more than 50% in 43.7% of patients. Greater improvement in the on state was observed in younger patients (r = −0.25; P < .01) with lower UPDRS II and III scores (r = −0.50; P < .01) and no antimuscarinic use (r = −0.21; P < .01). CONCLUSIONS AND RELEVANCE Freezing of gait in PD patients correlates with poor quality of life, disease severity, apathy, and exposure to antimuscarinics. Dopaminergic therapy improved FOG in most patients with motor fluctuations, especially younger ones with less severe disease and no antimuscarinic use. This finding suggests that quality of life is impaired in PD patients with FOG and that optimizing dopaminergic therapy and avoiding antimuscarinics should be considered.

show abstract

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Prevalence, Determinants, and Effect on Quality of Life of Freezing of Gait in Parkinson Disease

et al. 2014

View full text Add to dashboard Cite

show abstract

“…Cognitive assessment involved the application of the mini-mental state examination (MMSE),16 17 Frontal Assessment Battery (FAB),18 19 Executive Interview (EXIT25),20 21 Hachinski scale,15 Katz index of independence in activities of daily living22 and Pfeffer Functional Activities Questionnaire 23. Motor assessment included application of the Giladi’s FOG questionnaire (FOG-Q),24 25 Movement Disorders Society’s Unified PD Rating Scale (MDS-UPDRS),26 27 and HY stage,12 13 all in ‘ON’ and ‘OFF’ states. The presence of lower limb parkinsonism was determined by a two-point difference between upper limb and lower limb scores of bradykinesia, rigidity or postural instability from part III of the MDS-UPDRS 26 27.…”

Section: Methodsmentioning

confidence: 99%

Clinicoradiological comparison between vascular parkinsonism and Parkinson’s disease

Vale

Caramelli

Cardoso

2014

J Neurol Neurosurg Psychiatry

View full text Add to dashboard Cite

show abstract

“…the "OFF" period). Immediately afterwards, the FOG scale by Giladi et al 12,13 , which was recently translated into Portuguese 14 , was applied to all patients during the "OFF" period. Patients were instructed to use their re gular diurnal dose of levodopa and were evaluated with the aforementioned scales after an hour.…”

Section: Scales and Testsmentioning

confidence: 99%

Vascular parkinsonism: a case series of 17 patients

Vale

Caramelli

Cardoso

2013

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

Objective To report the clinical and neuroimaging findings in a case series of vascular parkinsonism (VP). Methods Seventeen patients with VP were evaluated with motor, cognitive, and neuroimaging standardized tests and scales. Results All patients had arterial hypertension. Ten patients were male and the mean age of the whole sample was 75.8±10.1 years. The mean age of parkinsonism onset was 72.2±10.0 years. Common clinical features were urinary incontinence (88.2%), lower limb parkinsonism with freezing of gait and falls (82.3%), and pyramidal signs (76.4%). The mean Unified Parkinson’s Disease Rating Scale (UPDRS) and Hoehn-Yahr scores were 72.5±21.6 points and 3.3±0.9 points, respectively. Sixteen (94.1%) patients had freezing of gait and executive dysfunction. Twelve (70.5%) patients had probable vascular dementia. The mean dose of levodopa was 530.9 mg/day. Unresponsiveness to the drug was confirmed by a 6.9 mean point reduction in the UPDRS score after the “practically defined off” test. Conclusion This series provides a profile of VP with predominant lower-limb involvement, freezing of gait and falls, pyramidal signs, executive dysfunction, concomitant vascular dementia, and poor levodopa response.

show abstract

Validity of the Brazilian version of the freezing of gait questionnaire

Cited by 31 publications

References 24 publications

Prevalence, Determinants, and Effect on Quality of Life of Freezing of Gait in Parkinson Disease

Prevalence, Determinants, and Effect on Quality of Life of Freezing of Gait in Parkinson Disease

Clinicoradiological comparison between vascular parkinsonism and Parkinson’s disease

Vascular parkinsonism: a case series of 17 patients

Contact Info

Product

Resources

About