Bithalamic compromise in acute disseminated encephalomyelitis following H1N1 influenza vaccine

Fernandes, Artur Furlaneto; Marchiori, Paulo Eurípedes

doi:10.1590/s0004-282x2011000400035

Cited by 11 publications

(6 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, the pattern of thalamic lesions in ADEM can be variable. Bilateral symmetric parts of the thalamus were most affected in this patient, which has not been reported in the previous literature as far as we know [1,10,11]. The involvement pattern in this patient was different from other pathology affecting certain other parts of the thalamus, including paramedian involvement for infarction of the Percheron artery, medial involvement for Wernicke encephalopathy, or ventrolateral involvement for Wilson's disease.…”

Section: Discussioncontrasting

confidence: 53%

Bilateral thalamic lesions in a patient with probable acute disseminating encephalomyelitis: a case report

et al. 2020

View full text Add to dashboard Cite

Background: Bilateral thalamic lesions are rare. Here, we describe a case of probable acute disseminating encephalomyelitis (ADEM) with symmetrical bilateral thalamic lesions. Case presentation: An 85-year-old man presented with weakness of the lower limbs and urinary retention for 1 day, soon followed by coma. He had an H1N1 influenza vaccination 3 months ago. A lumbar puncture showed positive oligoclonal bands and negative results for anti-AQP4 antibodies. A head MRI demonstrated focal symmetrical bilateral thalamic lesions. An MRI of the thoracic spinal cord showed longitudinally extensive lesions in the spinal cord. He was diagnosed with probable ADEM. Despite being treated with IVIG, the patient remained unconscious and died a month later from pneumonia. Conclusions: In cases with bilateral thalamic lesions, the possibility of ADEM should be considered. The characteristics of the thalamic lesions and imaging findings in other parts of the brain or spinal cord should be taken into account in association with the clinical and laboratory information in making a correct diagnosis.

show abstract

Section: Discussioncontrasting

confidence: 53%

Bilateral thalamic lesions in a patient with probable acute disseminating encephalomyelitis: a case report

et al. 2020

View full text Add to dashboard Cite

show abstract

“…The vaccine types used were trivalent inactivated influenza vaccine in two cases, liveattenuated influenza vaccine in one case, and unknown in one case. In the English literature, we found six case reports of ADEM (7)(8)(9)(10) and one case report of transverse myelitis (11). In Japan after the pandemic, 13 cases of ADEM after influenza vaccination were reported between November 1, 2010 and May 31, 2011 (12).…”

Section: Discussionmentioning

confidence: 99%

Acute Disseminated Encephalomyelitis Following 2009 H1N1 Influenza Vaccination

Maeda

Idehara

2012

Intern. Med.

View full text Add to dashboard Cite

Since the worldwide spread of the novel influenza type A virus in 2009, trivalent vaccines against H1N1 (pandemic) 09 and seasonal influenza have been used. We describe a 33-year-old woman who presented with hypoesthesia below the Th7 level fifteen days after vaccination without any preceding infection. Cerebrospinal fluid showed an increased level of myelin basic protein and positive oligoclonal IgG bands. Magnetic resonance imaging revealed disseminated lesions in the brain and thoracic cord. Steroid therapy improved her symptoms. She was diagnosed as having acute disseminated encephalomyelitis (ADEM) possibly related to the vaccination. As a potential adverse effect of the influenza vaccine, in addition to Guillain-Barré syndrome, ADEM should also be recognized.

show abstract

“…Influenza [17,18] HPV [19] Smallpox [20] Yellow fever [20] Rabies [20] Tuberculosis [20] Typhoid fever [20] HBV [21][22][23][24][25] Acute disseminated encephalomyelitis Rabies [26][27][28][29][30][31] Influenza [32][33][34][35][36][37][38][39][40][41][42][43][44][45][46][47][48][49][50][51] HPV [19,[52][53][54][55][56] Yellow fever [57] HBV [58,59] Hepatitis Tetanus toxoid [106] Cholera, typhoid, and polio [107] Measles …”

Section: Msmentioning

confidence: 99%