Rhombencephalitis possibly caused by Mycoplasma pneumoniae

Christo, Paulo Pereira; Silva, Júlio Sérgio P. da; Werneck, Ilana Vaula; Dias, Sandra Lucia

doi:10.1590/s0004-282x2010000400035

Cited by 8 publications

(8 citation statements)

References 12 publications

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“…The differential diagnosis of rhombencephalitis should include multiple sclerosis, Behcet's disease, paraneoplastic syndrome and other infectious diseases (Listeria monocytogenes, EBV, Mycoplasma etc). (6) Listerial rhombencephalitis has a characteristic biphasic course: for the first 2-4 days there are nonspecific symptoms, such as fever, headache, nausea and vomiting, followed by progressive asymmetrical cranial nerve palsies, cerebellar signs, hemiparesis and impairment of consciousness. The onset of neurological deterioration is usually abrupt.…”

Section: Discussionmentioning

confidence: 99%

Community-acquired Klebsiella pneumoniae systemic infection complicated with rhombencephalitis

Stanca

Bala²,

Rusca³

et al. 2020

Preprint

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Section: Discussionmentioning

confidence: 99%

Community-acquired Klebsiella pneumoniae systemic infection complicated with rhombencephalitis

Stanca

Bala²,

Rusca³

et al. 2020

Preprint

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“…The differential diagnosis for rhombencephalitis should include MS, Behcet disease, paraneoplastic syndrome, and other infections (EBV and Mycoplasma ) [22, 23]. …”

Section: Discussionmentioning

confidence: 99%

Listerial Rhombencephalitis in an Immunocompetent Woman

Czupryna

Zajkowska

Garkowski

et al. 2014

Case Reports in Neurological Medicine

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Listeriosis usually affects immunocompromised patients including elderly people and pregnant women, but it may also affect otherwise healthy individuals. In our report, we present a case of a rare and very severe form of listeriosis-rhombencephalitis in a 61-year-old female with no history of immunosuppression, who, because of history, clinical picture, and laboratory results as well as negative cultures, was at first diagnosed with viral encephalitis. This paper underlines that Listeria monocytogenes infection should be taken into consideration in case of lymphocytic encephalitis even in immunocompetent patients. Typical MRI picture may be crucial in establishing a proper diagnosis as the lab results may be misleading.

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“…The brain is the second most common site of Mycoplasma pneumoniae infection after the lungs [149] and evidence of infection is readily detected by T2-weighted magnetic resonance imaging (MRI) [150]. The organism is a known cause of Guillain-Barre syndrome and encephalitis in adults and children, likely via the secretion of a neurotoxin [149,151].…”

Section: Mycoplasmamentioning

confidence: 99%

“…The organism is a known cause of Guillain-Barre syndrome and encephalitis in adults and children, likely via the secretion of a neurotoxin [149,151]. A number of authors have also suggested a causative role in some patients with Mycoplasma species especially in females [152].…”

Section: Mycoplasmamentioning

confidence: 99%

The Putative Role of Viruses, Bacteria, and Chronic Fungal Biotoxin Exposure in the Genesis of Intractable Fatigue Accompanied by Cognitive and Physical Disability

Morris¹,

Berk

Walder

et al. 2015

Mol Neurobiol

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Patients who present with severe intractable apparently idiopathic fatigue accompanied by profound physical and or cognitive disability present a significant therapeutic challenge. The effect of psychological counseling is limited, with significant but very slight improvements in psychometric measures of fatigue and disability but no improvement on scientific measures of physical impairment compared to controls. Similarly, exercise regimes either produce significant, but practically unimportant, benefit or provoke symptom exacerbation. Many such patients are afforded the exclusionary, non-specific diagnosis of chronic fatigue syndrome if rudimentary testing fails to discover the cause of their symptoms. More sophisticated investigations often reveal the presence of a range of pathogens capable of establishing life-long infections with sophisticated immune evasion strategies, including Parvoviruses, HHV6, variants of Epstein-Barr, Cytomegalovirus, Mycoplasma, and Borrelia burgdorferi. Other patients have a history of chronic fungal or other biotoxin exposure. Herein, we explain the epigenetic factors that may render such individuals susceptible to the chronic pathology induced by such agents, how such agents induce pathology, and, indeed, how such pathology can persist and even amplify even when infections have cleared or when biotoxin exposure has ceased. The presence of active, reactivated, or even latent Herpes virus could be a potential source of intractable fatigue accompanied by profound physical and or cognitive disability in some patients, and the same may be true of persistent Parvovirus B12 and mycoplasma infection. A history of chronic mold exposure is a feasible explanation for such symptoms, as is the presence of B. burgdorferi. The complex tropism, life cycles, genetic variability, and low titer of many of these pathogens makes their detection in blood a challenge. Examination of lymphoid tissue or CSF in such circumstances may be warranted.

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Rhombencephalitis possibly caused by Mycoplasma pneumoniae

Cited by 8 publications

References 12 publications

Community-acquired Klebsiella pneumoniae systemic infection complicated with rhombencephalitis

Community-acquired Klebsiella pneumoniae systemic infection complicated with rhombencephalitis

Listerial Rhombencephalitis in an Immunocompetent Woman

The Putative Role of Viruses, Bacteria, and Chronic Fungal Biotoxin Exposure in the Genesis of Intractable Fatigue Accompanied by Cognitive and Physical Disability

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